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anti-GNPAT antibody :: Rabbit GNPAT Polyclonal Antibody

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Catalog # MBS129275
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.1 mL  /  $305 +1 FREE 8GB USB
  0.2 mL  /  $460 +1 FREE 8GB USB
Western Blot (WB)
Product Name

GNPAT, Polyclonal Antibody

Popular Item
Full Product Name

GNPAT Polyclonal Antibody

Product Synonym Names
DAPAT; DAP-AT; DHAPAT
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
phenotype 602744
3D Structure
ModBase 3D Structure for O15228
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Species
Human
Immunogen
Recombinant Protein
Immunogen
Recombinant protein of human GNPAT
Calculated Molecular Weight
77kDa
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Notes
Small volumes of anti-GNPAT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GNPAT antibody
This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata.
Product Categories/Family for anti-GNPAT antibody
Applications Tested/Suitable for anti-GNPAT antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-GNPAT antibody
WB: 1:500 - 1:2000
IF: 1:50 - 1:200

Western Blot (WB) of anti-GNPAT antibody
Western blot analysis of extracts of various cell lines, using GNPAT antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.
anti-GNPAT antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for GNPAT. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
680
NCBI Official Full Name
Dihydroxyacetone phosphate acyltransferase
NCBI Official Synonym Full Names
glyceronephosphate O-acyltransferase
NCBI Official Symbol
GNPAT  [Similar Products]
NCBI Official Synonym Symbols
DAPAT; DAP-AT; DHAPAT
  [Similar Products]
NCBI Protein Information
dihydroxyacetone phosphate acyltransferase; DHAP-AT; glycerone-phosphate O-acyltransferase; acyl-CoA:dihydroxyacetonephosphateacyltransferase
UniProt Protein Name
Dihydroxyacetone phosphate acyltransferase
UniProt Synonym Protein Names
Acyl-CoA:dihydroxyacetonephosphateacyltransferase; Glycerone-phosphate O-acyltransferase
UniProt Gene Name
GNPAT  [Similar Products]
UniProt Synonym Gene Names
DAPAT; DHAPAT; DAP-AT; DHAP-AT  [Similar Products]
UniProt Entry Name
GNPAT_HUMAN
NCBI Summary for GNPAT
This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata. [provided by RefSeq, Jul 2008]
UniProt Comments for GNPAT
GNPAT: Defects in GNPAT are the cause of rhizomelic chondrodysplasia punctata type 2 (RCDP2). RDCP2 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation. Belongs to the GPAT/DAPAT family.

Protein type: EC 2.3.1.42; Lipid Metabolism - glycerophospholipid; Transferase

Chromosomal Location of Human Ortholog: 1q42

Cellular Component: peroxisomal membrane; peroxisomal matrix; mitochondrion; membrane; peroxisome

Molecular Function: glycerone-phosphate O-acyltransferase activity; palmitoyl-CoA hydrolase activity; receptor binding

Biological Process: response to drug; response to starvation; synaptogenesis; phospholipid metabolic process; glycerophospholipid biosynthetic process; cerebellum morphogenesis; phosphatidic acid biosynthetic process; cellular lipid metabolic process; response to nutrient; ether lipid biosynthetic process; paranodal junction assembly

Disease: Rhizomelic Chondrodysplasia Punctata, Type 2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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