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anti-P2RY14 antibody :: Rabbit GPR105 Polyclonal Antibody

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Catalog # MBS820848
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

GPR105 (P2RY14), Polyclonal Antibody

Popular Item
Full Product Name

Anti-GPR105 Antibody

Product Synonym Names
GPR105; KIAA0001; P2Y purinoceptor 14; P2Y14; G-protein coupled receptor 105; UDP-glucose receptor
Antibody/Peptide Pairs
GPR105 peptide (MBS824060) is used for blocking the activity of GPR105 antibody (MBS820848)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
610116
3D Structure
ModBase 3D Structure for Q15391
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of GPR105 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GPR105. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-P2RY14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-P2RY14 antibody
Rabbit polyclonal antibody to GPR105
Applications Tested/Suitable for anti-P2RY14 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes for anti-P2RY14 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100)

Western Blot (WB) of anti-P2RY14 antibody
Western blot analysis of GPR105 expression in MDAMB435 (A), HEK293 (B) whole cell lysates.
anti-P2RY14 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-P2RY14 antibody
Immunohistochemical analysis of GPR105 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-P2RY14 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for P2RY14. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,971 Da
NCBI Official Full Name
P2Y purinoceptor 14
NCBI Official Synonym Full Names
purinergic receptor P2Y, G-protein coupled, 14
NCBI Official Symbol
P2RY14  [Similar Products]
NCBI Official Synonym Symbols
P2Y14; BPR105; GPR105
  [Similar Products]
NCBI Protein Information
P2Y purinoceptor 14; P2Y14 receptor; UDP-glucose receptor; G protein-coupled receptor 105; G-protein coupled receptor 105; G protein coupled receptor for UDP-glucose
UniProt Protein Name
P2Y purinoceptor 14
UniProt Synonym Protein Names
G-protein coupled receptor 105; UDP-glucose receptor
Protein Family
UniProt Gene Name
P2RY14  [Similar Products]
UniProt Synonym Gene Names
GPR105; KIAA0001; P2Y14  [Similar Products]
UniProt Entry Name
P2Y14_HUMAN
NCBI Summary for P2RY14
The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for P2RY14
P2RY14: Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3q24-q25.1

Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: UDP-activated nucleotide receptor activity; purinergic nucleotide receptor activity, G-protein coupled

Biological Process: G-protein coupled receptor protein signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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