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anti-GSDMD antibody :: Rabbit GSDMD Polyclonal Antibody

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Catalog # MBS9130687
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.1 mL  /  $305 +1 FREE 8GB USB
  0.2 mL  /  $460 +1 FREE 8GB USB
Western Blot (WB)
Product Name

GSDMD, Polyclonal Antibody

Popular Item
Full Product Name

GSDMD Polyclonal Antibody

Product Synonym Names
1810036L03Rik; AW558049; DF5L; Dfna5l; Gsdmdc1; M2-4
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS9130687 Technical Datasheet
3D Structure
ModBase 3D Structure for Q9D8T2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Immunogen
Recombinant fusion protein containin a sequence corresponding to amino acids 80-163 of mouse GSDMD (NP_081236.1).
Calculated MW
53kDa
Observed MW
53 kDa
Preparation and Storage
Store at -20°C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-GSDMD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-GSDMD antibody
Applications Tested/Suitable for anti-GSDMD antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-GSDMD antibody
WB: 1:500 - 1:2000
IF : 1:50-1:200

Western Blot (WB) of anti-GSDMD antibody
Western blot analysis of extracts of various cell lines, using GSDMD antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 60s.
anti-GSDMD antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for GSDMD. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Gasdermin-D
NCBI Official Synonym Full Names
gasdermin D
NCBI Official Symbol
Gsdmd  [Similar Products]
NCBI Official Synonym Symbols
DF5L; M2-4; Dfna5l; Gsdmdc1; AW558049; 1810036L03Rik
  [Similar Products]
NCBI Protein Information
gasdermin-D
UniProt Protein Name
Gasdermin-D
UniProt Synonym Protein Names
Gasdermin domain-containing protein 1
Protein Family
UniProt Gene Name
Gsdmdc1  [Similar Products]
UniProt Synonym Gene Names
Gsdmd; GSDMD-CT  [Similar Products]
UniProt Comments for GSDMD
FKSG10: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 15|15 D3

Cellular Component: cytosol; extracellular space; nucleoplasm; plasma membrane

Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding

Biological Process: cellular response to extracellular stimulus; cytolysis; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; pore complex biogenesis; positive regulation of interleukin-1 beta secretion; protein homooligomerization
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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