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anti-GSDMB antibody :: GSDML Polyclonal Antibody

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Catalog # MBS8245274
Unit / Price
  0.05 mL  /  $195 +1 FREE 8GB USB
  0.1 mL  /  $250 +1 FREE 8GB USB
  0.2 mL  /  $350 +1 FREE 8GB USB
Western Blot (WB)
Product Name

GSDML (GSDMB), Polyclonal Antibody

Popular Item
Also Known As

Anti-GSDML Antibody

Product Synonym Names
GSDML; Gasdermin-B; Gasdermin-like protein
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
403
OMIM
611221
3D Structure
ModBase 3D Structure for Q8TAX9
Clonality
Polyclonal
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of GSDML protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Source
Rabbit
Immunogen
Recombinant full length protein of human GSDML
Preparation and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-GSDMB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GSDMB antibody
Rabbit polyclonal antibody to GSDML
Applications Tested/Suitable for anti-GSDMB antibody
Western Blot (WB)
Application Notes for anti-GSDMB antibody
WB: 1/500 - 1/2000

Western Blot (WB) of anti-GSDMB antibody
Western blot analysis of GSDML expression in Hela (A), HT29 (B), mouse liver (C), rat liver (D) whole cell lysates.
anti-GSDMB antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for GSDMB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
gasdermin-B isoform 1
NCBI Official Synonym Full Names
gasdermin B
NCBI Official Symbol
GSDMB  [Similar Products]
NCBI Official Synonym Symbols
GSDML; PP4052; PRO2521
  [Similar Products]
NCBI Protein Information
gasdermin-B
UniProt Protein Name
Gasdermin-B
UniProt Synonym Protein Names
Gasdermin-like protein
Protein Family
UniProt Gene Name
GSDMB  [Similar Products]
UniProt Synonym Gene Names
GSDML  [Similar Products]
UniProt Entry Name
GSDMB_HUMAN
NCBI Summary for GSDMB
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Sep 2009]
UniProt Comments for GSDMB
GSDML: May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells. Belongs to the gasdermin family. 6 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: cytoplasm

Biological Process: programmed cell death
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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