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anti-GUCY1B3 antibody :: Rabbit guanylate cyclase 1, soluble, beta 3 Polyclonal Antibody

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Catalog # MBS711140
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-GUCY1B3 antibody
Product Name

guanylate cyclase 1, soluble, beta 3 (GUCY1B3), Polyclonal Antibody

Full Product Name

Rabbit anti-human guanylate cyclase 1, soluble, beta 3 polyclonal Antibody

Product Synonym Names
guanylate cyclase 1; soluble; beta 3; GUCY1B3; GC-S-beta-1; GC-SB3; GUC1B3; GUCB3; GUCSB3; GUCY1B1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
139397
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human GUCY1B3
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21309 / sc-21310 / sc-34431 / sc-34432 / sc-34430 / sc-20955
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-GUCY1B3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GUCY1B3 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
NCBI/Uniprot data below describe general gene information for GUCY1B3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
68,165 Da[Similar Products]
NCBI Official Full Name
Guanylate cyclase 1, soluble, beta 3
NCBI Official Synonym Full Names
guanylate cyclase 1, soluble, beta 3
NCBI Official Symbol
GUCY1B3  [Similar Products]
NCBI Official Synonym Symbols
GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B1; GC-S-beta-1
  [Similar Products]
NCBI Protein Information
guanylate cyclase soluble subunit beta-1; GCS-beta-1; GCS-beta-3; soluble guanylate cyclase small subunit; guanylate cyclase soluble subunit beta-3
UniProt Protein Name
Guanylate cyclase soluble subunit beta-1
UniProt Synonym Protein Names
Guanylate cyclase soluble subunit beta-3; GCS-beta-3; Soluble guanylate cyclase small subunit
Protein Family
UniProt Gene Name
GUCY1B3  [Similar Products]
UniProt Synonym Gene Names
GUC1B3; GUCSB3; GUCY1B1; GCS-beta-1; GCS-beta-3  [Similar Products]
UniProt Entry Name
GCYB1_HUMAN
NCBI Summary for GUCY1B3
This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
UniProt Comments for GUCY1B3
GUCY1B3: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Heterodimer of an alpha and a beta chain. 2 isoforms of the human protein are produced by alternative splicing

Protein type: Lyase; EC 4.6.1.2; Nucleotide Metabolism - purine; Guanylyl cyclase; Receptor, misc.

Chromosomal Location of Human Ortholog: 4q31.3-q33

Cellular Component: guanylate cyclase complex, soluble; intracellular membrane-bound organelle; cytoplasm

Molecular Function: guanylate cyclase activity; GTP binding; protein heterodimerization activity; metal ion binding; heme binding; receptor activity; Hsp90 protein binding

Biological Process: cGMP biosynthetic process; blood circulation; blood coagulation; nitric oxide mediated signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-GUCY1B3 antibody
 Reference Product  PubMed Publications
 GUCY1A3 antibody  >5 publications with GUCY1B3 and GUCY1A3
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