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anti-C1R antibody :: Rabbit HIC2 Polyclonal Antibody

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Catalog # MBS9207189
Unit / Price
  0.1 mL  /  $340 +1 FREE 8GB USB
Western Blot (WB)
Product Name

HIC2 (C1R), Polyclonal Antibody

Popular Item
Also Known As

HIC2 Antibody

Product Synonym Names
Complement C1r subcomponent; Complement component 1 subcomponent r; Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain; C1R
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
421-480
Immunogen Sequence Length
705
OMIM
216950
3D Structure
ModBase 3D Structure for P00736
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, mouse, rat
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
Concentration
1mg/ml (lot specific)
Cellular Location
Secreted
Preparation and Storage
Store at -20 degree C.Stable for 12 months from date of receipt
Other Notes
Small volumes of anti-C1R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-C1R antibody
C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Product Categories/Family for anti-C1R antibody
Applications Tested/Suitable for anti-C1R antibody
Western Blot (WB)
Application Notes for anti-C1R antibody
WB~~ 1:1000

Western Blot (WB) of anti-C1R antibody
Anti-HIC2 Antibody at 1:1000 dilution + HeLa whole cell lysates

Lysates/proteins at 20 ug per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution

Predicted band size : 66 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.
anti-C1R antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for C1R. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
66,64 KDa
NCBI Official Full Name
complement C1r subcomponent
NCBI Official Synonym Full Names
complement component 1, r subcomponent
NCBI Official Symbol
NCBI Protein Information
complement C1r subcomponent
UniProt Protein Name
Complement C1r subcomponent
UniProt Synonym Protein Names
Complement component 1 subcomponent r
UniProt Gene Name
UniProt Entry Name
C1R_HUMAN
UniProt Comments for C1R
C1R: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. Belongs to the peptidase S1 family.

Protein type: Protease; EC 3.4.21.41

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: extracellular region

Molecular Function: protein binding; serine-type peptidase activity; serine-type endopeptidase activity; calcium ion binding

Biological Process: innate immune response; immune response; proteolysis; complement activation, classical pathway; complement activation

Disease: Complement Component C1r/c1s Deficiency
Product References and Citations for anti-C1R antibody
Leytus S.P.,et al.Biochemistry 25:4855-4863(1986).
Journet A.,et al.Biochem. J. 240:783-787(1986).
Nakagawa M.,et al.Ann. Hum. Genet. 67:207-215(2003).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Scherer S.E.,et al.Nature 440:346-351(2006).

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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