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anti-HK3 antibody :: Rabbit HK3 Polyclonal Antibody

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Catalog # MBS2525851
Unit / Price
  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Product Name

HK3, Polyclonal Antibody

Popular Item
Full Product Name

HK3 Polyclonal Antibody

Product Synonym Names
HXK3; HKIII
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
142570
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
2.5mg/mL (lot specific)
Immunogen
Recombinant protein of human HK3
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-HK3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HK3 antibody
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate.
Applications Tested/Suitable for anti-HK3 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-HK3 antibody
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-HK3 antibody
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using HK3 Polyclonal Antibody at dilution 1:40
anti-HK3 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-HK3 antibody
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using HK3 Polyclonal Antibody at dilution 1:40
anti-HK3 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for HK3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
99,025 Da
NCBI Official Full Name
hexokinase-3
NCBI Official Synonym Full Names
hexokinase 3 (white cell)
NCBI Official Symbol
NCBI Official Synonym Symbols
HXK3; HKIII
  [Similar Products]
NCBI Protein Information
hexokinase-3; ATP:D-hexose 6-phosphotransferase; HK III; hexokinase type III
UniProt Protein Name
Hexokinase-3
UniProt Synonym Protein Names
Hexokinase type III; HK III
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
HK III  [Similar Products]
UniProt Entry Name
HXK3_HUMAN
NCBI Summary for HK3
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. [provided by RefSeq, Apr 2009]
UniProt Comments for HK3
HK3: a glycolytic enzyme that catalyzes the reaction ATP + D-hexose = ADP + D-hexose 6-phosphate. The first and rate-limiting step in glycosis, a pathway that produces energy in the form of ATP from glucose. An allosteric enzyme inhibited by its product glucose-6-phosphate (Glc-6-P). Acts as a ""glucose sensor"" by trapping glucose inside the cell by catalyzing its phosphorylation to produce Glc-6-P. In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).

Protein type: EC 2.7.1.1; Transferase; Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Enzyme, cellular metabolism; Kinase, other; Carbohydrate Metabolism - glycolysis and gluconeogenesis

Chromosomal Location of Human Ortholog: 5q35.2

Cellular Component: protein complex; mitochondrion; cytosol

Molecular Function: hexokinase activity; enzyme binding; mannokinase activity; hormone binding; fructokinase activity; glucokinase activity; ATP binding

Biological Process: hexose metabolic process; glycolysis; hexose transport; carbohydrate metabolic process; glucose 6-phosphate metabolic process; carbohydrate phosphorylation; cell glucose homeostasis; pathogenesis; glucose transport; transmembrane transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-HK3 antibody
 Reference Product  PubMed Publications
 PFKFB2 antibody  >1 publications with HK3 and PFKFB2
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