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anti-HNRNPC antibody :: Rabbit HNRNPC Polyclonal Antibody

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Catalog # MBS2542995
Unit / Price
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  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Western Blot (WB)
Product Name

HNRNPC, Polyclonal Antibody

Popular Item
Full Product Name

HNRNPC Polyclonal Antibody

Product Synonym Names
C1; C2; HNRNP; HNRPC; SNRPC
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
M29063 mRNA
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purification
Concentration
2mg/ml (lot specific)
Immunogen
Synthetic peptide of human HNRNPC
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10041 / sc-10037 / sc-15386
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-HNRNPC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HNRNPC antibody
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. 
Applications Tested/Suitable for anti-HNRNPC antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-HNRNPC antibody
ELISA: 1:1000-2000
WB: 1:200-1000

Western Blot (WB) of anti-HNRNPC antibody
Western Blot analysis of K562 cell using HNRNPC Polyclonal Antibody at dilution of 1/200
anti-HNRNPC antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for HNRNPC. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
34 kDa
NCBI Official Full Name
heterogeneous nuclear ribonucleoproteins C1/C2 isoform b
NCBI Official Synonym Full Names
heterogeneous nuclear ribonucleoprotein C (C1/C2)
NCBI Official Symbol
HNRNPC  [Similar Products]
NCBI Official Synonym Symbols
C1; C2; HNRNP; HNRPC; SNRPC
  [Similar Products]
NCBI Protein Information
heterogeneous nuclear ribonucleoproteins C1/C2
UniProt Protein Name
Heterogeneous nuclear ribonucleoproteins C1/C2
UniProt Gene Name
HNRNPC  [Similar Products]
UniProt Synonym Gene Names
HNRPC; hnRNP C1/C2  [Similar Products]
UniProt Entry Name
HNRPC_HUMAN
NCBI Summary for HNRNPC
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for HNRNPC
hnRNP C1/C2: a heterogeneous nuclear ribonucleoprotein. May play a role in ribonucleosome assembly by neutralizing basic proteins such as A and B core hnRNP. Contains 1 RNA recognition motif (RRM) domain. Two alternatively spliced isoforms have been described.

Protein type: RNA splicing; RNA-binding; Spliceosome

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: cytosol; membrane; nuclear chromatin; nucleoplasm; nucleus; protein complex; spliceosome; telomerase holoenzyme complex

Molecular Function: identical protein binding; mRNA 3'-UTR binding; nucleosomal DNA binding; poly(U) binding; protein binding

Biological Process: ATP-dependent chromatin remodeling; gene expression; negative regulation of telomere maintenance via telomerase; nuclear mRNA splicing, via spliceosome; osteoblast differentiation; protein sumoylation; RNA splicing
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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