• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-INPP5K antibody :: Rabbit inositol polyphosphate-5-phosphatase K Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS712890
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-INPP5K antibody
Product Name

inositol polyphosphate-5-phosphatase K (INPP5K), Polyclonal Antibody

Full Product Name

Rabbit anti-human inositol polyphosphate-5-phosphatase K polyclonal Antibody

Product Synonym Names
inositol polyphosphate-5-phosphatase K; INPP5K; PPS; SKIP
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
607875
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human INPP5K
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-12071 / sc-12073
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-INPP5K antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-INPP5K antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for INPP5K. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,784 Da[Similar Products]
NCBI Official Full Name
Inositol polyphosphate-5-phosphatase K
NCBI Official Synonym Full Names
inositol polyphosphate-5-phosphatase K
NCBI Official Symbol
INPP5K  [Similar Products]
NCBI Official Synonym Symbols
PPS; SKIP
  [Similar Products]
NCBI Protein Information
inositol polyphosphate 5-phosphatase K; skeletal muscle and kidney-enriched inositol phosphatase
UniProt Protein Name
Inositol polyphosphate 5-phosphatase K
UniProt Synonym Protein Names
Skeletal muscle and kidney-enriched inositol phosphatase
UniProt Gene Name
INPP5K  [Similar Products]
UniProt Synonym Gene Names
PPS; SKIP  [Similar Products]
UniProt Entry Name
INP5K_HUMAN
NCBI Summary for INPP5K
This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
UniProt Comments for INPP5K
INPP5K: Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5- trisphosphate. May negatively regulate assembly of the actin cytoskeleton. Belongs to the inositol 1,4,5-trisphosphate 5- phosphatase type II family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.56; Carbohydrate Metabolism - inositol phosphate; Phosphatase (non-protein)

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: ruffle; neuron projection; membrane; endoplasmic reticulum; perinuclear region of cytoplasm; cytoplasm; plasma membrane; trans-Golgi network; nucleus; cytosol

Molecular Function: protein binding; inositol trisphosphate phosphatase activity; inositol-polyphosphate 5-phosphatase activity; lipid phosphatase activity; inositol bisphosphate phosphatase activity; vasopressin receptor activity

Biological Process: negative regulation of retroviral genome replication; negative regulation of MAP kinase activity; negative regulation of calcium ion transport; negative regulation of protein kinase B signaling cascade; negative regulation of stress fiber formation; in utero embryonic development; positive regulation of transcription, DNA-dependent; regulation of glycogen biosynthetic process; negative regulation of peptidyl-serine phosphorylation; negative regulation of insulin receptor signaling pathway; glucose homeostasis; cellular response to hormone stimulus; G-protein coupled receptor protein signaling pathway; negative regulation of protein amino acid phosphorylation; cellular response to insulin stimulus; dephosphorylation; inositol phosphate dephosphorylation; negative regulation of dephosphorylation; phospholipid metabolic process; phosphatidylinositol biosynthetic process; phosphoinositide dephosphorylation; negative regulation of protein kinase activity; actin cytoskeleton organization and biogenesis; negative regulation of transcription, DNA-dependent; negative regulation of glycogen biosynthetic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-INPP5K antibody
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with INPP5K and Kidney
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000