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anti-INTS3 antibody :: Rabbit integrator complex subunit 3 Polyclonal Antibody

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Catalog # MBS710662
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-INTS3 antibody
Product Name

integrator complex subunit 3 (INTS3), Polyclonal Antibody

Also Known As

Rabbit anti-human integrator complex subunit 3 polyclonal Antibody

Product Synonym Names
integrator complex subunit 3; INTS3; C1orf193; C1orf60; DKFZp686E1950; DKFZp686O20115; DKFZp781I1253; FLJ21919; FLJ44849; INT3
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1042
OMIM
611347
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human INTS3
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-138355
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-INTS3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-INTS3 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for INTS3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
63,586 Da[Similar Products]
NCBI Official Full Name
integrator complex subunit 3
NCBI Official Synonym Full Names
integrator complex subunit 3
NCBI Official Symbol
INTS3  [Similar Products]
NCBI Official Synonym Symbols
INT3; SOSSA; SOSS-A; C1orf60; C1orf193
  [Similar Products]
NCBI Protein Information
integrator complex subunit 3; sensor of ssDNA A; SOSS complex subunit A; sensor of ssDNA subunit A; sensor of single-strand DNA complex subunit A
UniProt Protein Name
Integrator complex subunit 3
UniProt Synonym Protein Names
SOSS complex subunit A; Sensor of single-strand DNA complex subunit A; SOSS-A; Sensor of ssDNA subunit A
Protein Family
UniProt Gene Name
INTS3  [Similar Products]
UniProt Synonym Gene Names
C1orf193; C1orf60; Int3; SOSS-A; Sensor of ssDNA subunit A  [Similar Products]
UniProt Entry Name
INT3_HUMAN
NCBI Summary for INTS3
INTS3 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]). INTS3 is also a subunit of single-stranded DNA (ssDNA)-binding complexes involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]
UniProt Comments for INTS3
INTS3: Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Belongs to the Integrator subunit 3 family. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: nucleus; integrator complex

Molecular Function: protein binding

Biological Process: mitotic cell cycle checkpoint; snRNA processing; response to ionizing radiation; DNA repair; response to DNA damage stimulus
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-INTS3 antibody
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