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anti-IFITM3 antibody :: Rabbit interferon induced transmembrane protein 3 Polyclonal Antibody

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Catalog # MBS714813
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-IFITM3 antibody
Product Name

interferon induced transmembrane protein 3 (IFITM3), Polyclonal Antibody

Also Known As

Rabbit anti-human interferon induced transmembrane protein 3 (1-8U) polyclonal Antibody

Product Synonym Names
interferon induced transmembrane protein 3 (1-8U); IFITM3; 1-8U; IP15
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
133
OMIM
gene 614680
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human IFITM3
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-130785
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-IFITM3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-IFITM3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for IFITM3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,632 Da[Similar Products]
NCBI Official Full Name
interferon-induced transmembrane protein 3
NCBI Official Synonym Full Names
interferon induced transmembrane protein 3
NCBI Official Symbol
IFITM3  [Similar Products]
NCBI Official Synonym Symbols
1-8U; IP15; DSPA2b
  [Similar Products]
NCBI Protein Information
interferon-induced transmembrane protein 3; dispanin subfamily A member 2b; interferon-inducible protein 1-8U
UniProt Protein Name
Interferon-induced transmembrane protein 3
UniProt Synonym Protein Names
Dispanin subfamily A member 2b; DSPA2b; Interferon-inducible protein 1-8U
UniProt Gene Name
IFITM3  [Similar Products]
UniProt Synonym Gene Names
DSPA2b  [Similar Products]
UniProt Entry Name
IFM3_HUMAN
NCBI Summary for IFITM3
The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012]
UniProt Comments for IFITM3
IFITM3: IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. Interacts with SPP1; the interaction reduces OPN expression. By IFN-alpha and IFNG/IFN-gamma. Belongs to the CD225/Dispanin family.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: lysosomal membrane; late endosome membrane; integral to membrane; plasma membrane

Molecular Function: protein binding

Biological Process: negative regulation of viral transcription; negative regulation of viral genome replication; negative regulation of virion penetration into host cell; cytokine and chemokine mediated signaling pathway; response to virus; immune response; defense response to virus

Disease: Influenza, Severe, Susceptibility To
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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