NP_001305114.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 126 kDa Predicted: 127 kDa
NCBI Official Full Name
integrin alpha-D isoform 1
NCBI Official Synonym Full Names
integrin subunit alpha D
NCBI Official Synonym Symbols
NCBI Protein Information
integrin alpha-D
UniProt Protein Name
Integrin alpha-D
UniProt Synonym Protein Names
ADB2; CD11 antigen-like family member D; Leukointegrin alpha D; CD_antigen: CD11d
NCBI Summary for ITGAD
This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
UniProt Comments for ITGAD
Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood.
Research Articles on ITGAD
Precautions
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Products associated with anti-ITGAD antibody
Pathways associated with anti-ITGAD antibody
Diseases associated with anti-ITGAD antibody
Organs/Tissues associated with anti-ITGAD antibody
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