NP_001106212.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 60 kD Predicted: 58 kDa
NCBI Official Full Name
potassium voltage-gated channel subfamily C member 1 isoform 1
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily C member 1
NCBI Protein Information
potassium voltage-gated channel subfamily C member 1
UniProt Protein Name
Potassium voltage-gated channel subfamily C member 1
UniProt Synonym Protein Names
NGK2; Voltage-gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv4
NCBI Summary for KCNC1
This gene encodes a member of a family of integral membrane proteins that mediate the voltage-dependent potassium ion permeability of excitable membranes. Alternative splicing is thought to result in two transcript variants encoding isoforms that differ at their C-termini. These isoforms have had conflicting names in the literature: the longer isoform has been called both "b" and "alpha", while the shorter isoform has been called both "a" and "beta" (PMIDs 1432046, 12091563). [provided by RefSeq, Oct 2014]
UniProt Comments for KCNC1
Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient (PubMed:25401298). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons.
Research Articles on KCNC1
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Products associated with anti-KCNC1 antibody
Pathways associated with anti-KCNC1 antibody
Diseases associated with anti-KCNC1 antibody
Organs/Tissues associated with anti-KCNC1 antibody
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