NP_002229.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 111 kD Predicted: 112 kDa
NCBI Official Full Name
potassium voltage-gated channel subfamily H member 1 isoform 2
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily H member 1
NCBI Official Synonym Symbols
EAG; EAG1; ZLS1; TMBTS; h-eag; hEAG1; Kv10.1 [Similar Products]
NCBI Protein Information
potassium voltage-gated channel subfamily H member 1
UniProt Protein Name
Potassium voltage-gated channel subfamily H member 1
UniProt Synonym Protein Names
Ether-a-go-go potassium channel 1
UniProt Synonym Gene Names
EAG1 PublicationManual assertion based on opinion iniRef.2; EAG channel 12 PublicationsManual assertion based on opinion iniRef.12; h-eag; hEAG12 PublicationsManual assertion based on opinion iniRef.12 [Similar Products]
NCBI Summary for KCNH1
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
UniProt Comments for KCNH1
Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel (PubMed:9738473, PubMed:11943152, PubMed:10880439, PubMed:22732247, PubMed:25556795, PubMed:27325704, PubMed:27005320, PubMed:27618660). Channel properties are modulated by subunit assembly (PubMed:11943152). Mediates IK(NI) current in myoblasts (PubMed:9738473). Involved in the regulation of cell proliferation and differentiation, in particular adipogenic and osteogenic differentiation in bone marrow-derived mesenchymal stem cells (MSCs) (PubMed:23881642).
Research Articles on KCNH1
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Products associated with anti-KCNH1 antibody
Pathways associated with anti-KCNH1 antibody
Diseases associated with anti-KCNH1 antibody
Organs/Tissues associated with anti-KCNH1 antibody
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