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anti-KAT2A antibody :: Rabbit K(lysine) acetyltransferase 2A Polyclonal Antibody

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Catalog # MBS710485
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-KAT2A antibody
Product Name

K(lysine) acetyltransferase 2A (KAT2A), Polyclonal Antibody

Full Product Name

Rabbit anti-human K(lysine) acetyltransferase 2A polyclonal Antibody

Product Synonym Names
K(lysine) acetyltransferase 2A; KAT2A; GCN5; GCN5L2; MGC102791; PCAF-b; hGCN5
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
602301
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human KAT2A
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-6303 / sc-6302 / sc-20698
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-KAT2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-KAT2A antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for KAT2A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,921 Da[Similar Products]
NCBI Official Full Name
K(lysine) acetyltransferase 2A
NCBI Official Synonym Full Names
K(lysine) acetyltransferase 2A
NCBI Official Symbol
KAT2A  [Similar Products]
NCBI Official Synonym Symbols
GCN5; hGCN5; GCN5L2; PCAF-b
  [Similar Products]
NCBI Protein Information
histone acetyltransferase KAT2A; STAF97; hsGCN5; lysine acetyltransferase 2A; histone acetyltransferase GCN5; general control of amino acid synthesis protein 5-like 2; General control of amino acid synthesis, yeast, homolog-like 2; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2
UniProt Protein Name
Histone acetyltransferase KAT2A
UniProt Synonym Protein Names
General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; HsGCN5; Lysine acetyltransferase 2A; STAF97
Protein Family
UniProt Gene Name
KAT2A  [Similar Products]
UniProt Synonym Gene Names
GCN5; GCN5L2; HGCN5; HsGCN5  [Similar Products]
UniProt Entry Name
KAT2A_HUMAN
NCBI Summary for KAT2A
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009]
UniProt Comments for KAT2A
GCN5: an ubiquitous histone acetyltransferase that promotes transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. Interacts with P300, CBP, ADA2, and is a component of the TFTC-HAT complex. Two splice variant isoforms have been described.

Protein type: EC 2.3.1.48; Acetyltransferase

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: nucleoplasm; extracellular space

Molecular Function: protein binding; histone acetyltransferase activity; histone deacetylase binding; transcription coactivator activity; chromatin binding; H3 histone acetyltransferase activity

Biological Process: transcription from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; somitogenesis; viral reproduction; in utero embryonic development; multicellular organism growth; regulation of protein stability; metencephalon development; histone deubiquitination; chromatin remodeling; regulation of transcription from RNA polymerase II promoter; cell proliferation; telencephalon development; midbrain development; neural tube closure
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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