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anti-LINGO1 antibody :: Rabbit leucine rich repeat and Ig domain containing 1 Polyclonal Antibody

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Catalog # MBS711412
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-LINGO1 antibody
Product Name

leucine rich repeat and Ig domain containing 1 (LINGO1), Polyclonal Antibody

Full Product Name

Rabbit anti-human leucine rich repeat and Ig domain containing 1 polyclonal Antibody

Product Synonym Names
leucine rich repeat and Ig domain containing 1; LINGO1; FLJ14594; LERN1; LRRN6A; MGC17422; UNQ201
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
609791
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human LINGO1
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-LINGO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-LINGO1 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for LINGO1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
69,146 Da[Similar Products]
NCBI Official Full Name
Leucine rich repeat and Ig domain containing 1
NCBI Official Synonym Full Names
leucine rich repeat and Ig domain containing 1
NCBI Official Symbol
LINGO1  [Similar Products]
NCBI Official Synonym Symbols
LERN1; LRRN6A; UNQ201
  [Similar Products]
NCBI Protein Information
leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine rich repeat neuronal 6A; leucine-rich repeat neuronal protein 1; leucine-rich repeat and immunoglobulin domain-containing protein 1
UniProt Protein Name
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
UniProt Synonym Protein Names
Leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A
UniProt Gene Name
LINGO1  [Similar Products]
UniProt Synonym Gene Names
LERN1; LRRN6A  [Similar Products]
UniProt Entry Name
LIGO1_HUMAN
UniProt Comments for LINGO1
LINGO1: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q24.3

Cellular Component: plasma membrane; integral to membrane

Molecular Function: epidermal growth factor receptor binding

Biological Process: negative regulation of oligodendrocyte differentiation; nerve growth factor receptor signaling pathway; protein kinase B signaling cascade; negative regulation of axonogenesis; regulation of axonogenesis; neurite development; central nervous system neuron development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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