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anti-LIPH antibody :: Rabbit LIPH Polyclonal Antibody

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Catalog # MBS7601028
Unit / Price
  0.1 mg  /  $265 +1 FREE 8GB USB
anti-LIPH antibody
Product Name

LIPH, Polyclonal Antibody

Full Product Name

LIPH Rabbit Polyclonal

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
604379
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Immunogen
Lipase, member H
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-LIPH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-LIPH antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
NCBI/Uniprot data below describe general gene information for LIPH. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
50,859 Da
NCBI Official Full Name
LIPH, partial
NCBI Official Synonym Full Names
lipase H
NCBI Official Symbol
NCBI Official Synonym Symbols
AH; LAH2; ARWH2; HYPT7; LPDLR; PLA1B; mPA-PLA1
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NCBI Protein Information
lipase member H
UniProt Protein Name
Lipase member H
UniProt Synonym Protein Names
LPD lipase-related protein; Membrane-associated phosphatidic acid-selective phospholipase A1-alpha; mPA-PLA1 alpha; Phospholipase A1 member B
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
LPDLR; MPAPLA1; PLA1B; LIPH; mPA-PLA1 alpha  [Similar Products]
UniProt Entry Name
LIPH_HUMAN
NCBI Summary for LIPH
This gene encodes a membrane-bound member of the mammalian triglyceride lipase family. It catalyzes the production of 2-acyl lysophosphatidic acid (LPA), which is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility. [provided by RefSeq, Jul 2008]
UniProt Comments for LIPH
LIPH: Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG). Defects in LIPH are the cause of hypotrichosis type 7 (HYPT7); also known as alopecia universalis congenita Mari type. A condition characterized by the presence of less than the normal amount of hair. Affected individuals have sparse or absent scalp, axillary and body hair and sparse eyebrows and eyelashes. Defects in LIPH are the cause of woolly hair autosomal recessive type 2 (ARWH2). A hair shaft disorder characterized by fine and tightly curled hair. Compared to normal curly hair that is observed in some populations, woolly hair grows slowly and stops growing after a few inches. Under light microscopy, woolly hair shows some structural anomalies, including trichorrhexis nodosa and tapered ends. Some individuals may present with hypotrichosis. Belongs to the AB hydrolase superfamily. Lipase family.

Protein type: EC 3.1.1.-; Secreted, signal peptide; Secreted; Phospholipase

Chromosomal Location of Human Ortholog: 3q27

Cellular Component: extracellular space; plasma membrane

Molecular Function: heparin binding; phospholipase activity

Biological Process: lipid catabolic process; lipid digestion

Disease: Hypotrichosis 7
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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