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anti-MRPL22 antibody :: Rabbit MRPL22 Polyclonal Antibody

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Catalog # MBS9605121
Unit / Price
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  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

MRPL22, Polyclonal Antibody

Popular Item
Full Product Name

MRPL22 Antibody

Product Synonym Names
MRPL22; 39S ribosomal protein L22; 39S ribosomal protein L22 mitochondrial precursor; 39S ribosomal protein L25; 39S ribosomal protein L25, mitochondrial; E030011D16Rik; HSPC158; L22mt; L25mt; mitochondrial; mitochondrial ribosomal protein L22; MRP L22; MRP L25; MRP-L22; MRP-L25; Mrpl22; RM22_HUMAN; RPML25
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9NWU5
Species Reactivity
Human, Mouse, Rat
MRPL22 antibody detects endogenous levels of total MRPL22
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1mg/ml (lot specific)
A synthesized peptide
Subcellular Location
Predicted Cross Reactivity
Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken
Pig (100%), Zebrafish (92%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (85%)
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-MRPL22 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MRPL22 antibody
Subunit Structure: Component of the mitochondrial large ribosomal subunit (mt-LSU). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins.
Similarity: Belongs to the universal ribosomal protein uL22 family.
Applications Tested/Suitable for anti-MRPL22 antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
Application Notes for anti-MRPL22 antibody
WB: 1:500-1:1000
IF/ICC: 1:100-1:500

Immunofluorescence (IF) of anti-MRPL22 antibody
MBS9605121 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
anti-MRPL22 antibody Immunofluorescence (IF) image
Western Blot (WB) of anti-MRPL22 antibody
Western blot analysis of extracts from HepG2 cells, using MRPL22 antibody.
anti-MRPL22 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for MRPL22. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 24 kD
Predicted: 24 kDa
NCBI Official Full Name
39S ribosomal protein L22, mitochondrial isoform b
NCBI Official Synonym Full Names
mitochondrial ribosomal protein L22
NCBI Official Symbol
MRPL22  [Similar Products]
NCBI Official Synonym Symbols
L22mt; RPML25; HSPC158; MRP-L22; MRP-L25
  [Similar Products]
NCBI Protein Information
39S ribosomal protein L22, mitochondrial
UniProt Protein Name
39S ribosomal protein L22, mitochondrial
UniProt Synonym Protein Names
39S ribosomal protein L25, mitochondrial; L25mt; MRP-L25; Mitochondrial large ribosomal subunit protein uL22m
Protein Family
UniProt Gene Name
MRPL22  [Similar Products]
UniProt Synonym Gene Names
MRPL25; RPML25; L22mt; MRP-L22; L25mt; MRP-L25  [Similar Products]
NCBI Summary for MRPL22
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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Pathways associated with anti-MRPL22 antibody
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