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anti-MBP antibody :: Rabbit Myelin basic protein Polyclonal Antibody

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Catalog # MBS7601698 (SPECIAL PROMOTIONAL PRICING for a limited time)
Unit / Price
  0.1 mg  /  $180 +1 FREE 8GB USB
Product Name

Myelin basic protein (MBP), Polyclonal Antibody

Popular Item
Also Known As

Myelin basic protein Rabbit Polyclonal

Product Synonym Names
MBP, Myelin A1 protein, Myelin basic protein.
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS7601698 Technical Datasheet
Immunogen Sequence Length
203
OMIM
159430
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat. Other species are not tested.
Specificity
Please decide specifity by homology.
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Immunogen
Myelin basic protein
Calculated MW
34 kDa
Preparation and Storage
Store at -20°C for 24 months. (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-MBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-MBP antibody
ELISA, WB, IHC, IF
Application Notes for anti-MBP antibody
WB 1:500-1-2000
IHC 1:50-1:200
IF 1:50-1:200

Immunohistochemistry IHC of anti-MBP antibody
Immunohistochemistry of paraffin- embedded rat kidney tissue slide using MBS7601698( MBP Antibody) at dilution of 1:200
anti-MBP antibody Immunohistochemistry IHC (IHC) image
Testing Data TD of anti-MBP antibody
Mouse brain tissue were subjected to SDS PAGE followed by Western Blot with MBS7601698 (MBP Antibody) at dilution of 1:1000
anti-MBP antibody Testing Data TD image
NCBI/Uniprot data below describe general gene information for MBP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
myelin basic protein
NCBI Official Synonym Full Names
myelin basic protein
NCBI Official Symbol
NCBI Protein Information
Golli-MBP; myelin basic protein
UniProt Protein Name
Myelin basic protein
UniProt Synonym Protein Names
Myelin A1 protein; Myelin membrane encephalitogenic protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
MBP_HUMAN
NCBI Summary for MBP
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]
UniProt Comments for MBP
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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