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anti-MYH1 antibody :: Myosin 1 Polyclonal Antibody

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Catalog # MBS8247508
Unit / Price
  0.05 mL  /  $195 +1 FREE 8GB USB
  0.1 mL  /  $250 +1 FREE 8GB USB
  0.2 mL  /  $350 +1 FREE 8GB USB
Product Name

Myosin 1 (MYH1), Polyclonal Antibody

Popular Item
Full Product Name

Anti-Myosin 1 Antibody

Product Synonym Names
Myosin-1; Myosin heavy chain 1; Myosin heavy chain 2x; MyHC-2x; Myosin heavy chain IIx/d; MyHC-IIx/d; Myosin heavy chain, skeletal muscle, adult 1
Product Gene Name

anti-MYH1 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
160730
3D Structure
ModBase 3D Structure for P12882
Clonality
Polyclonal
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of Myosin 1 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Source
Rabbit
Immunogen
Recombinant full length protein of human Myosin 1
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-MYH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-MYH1 antibody
Rabbit polyclonal antibody to Myosin 1
Applications Tested/Suitable for anti-MYH1 antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-MYH1 antibody
WB: 1/500 - 1/2000; IF/IC: 1/50 - 1/100
Western Blot (WB) of anti-MYH1 antibody
Western blot analysis of Myosin 1 expression in mouse heart (A), rat skeletal muscle (B), rat heart (C) whole cell lysates.
anti-MYH1 antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-MYH1 antibody
Immunofluorescent analysis of Myosin 1 staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 degree C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
anti-MYH1 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for MYH1. It may not necessarily be applicable to this product.
NCBI GI #
115527082
NCBI GeneID
4619
NCBI Accession #
NP_005954.3 [Other Products]
NCBI GenBank Nucleotide #
NM_005963.3 [Other Products]
UniProt Primary Accession #
P12882 [Other Products]
UniProt Secondary Accession #
Q14CA4; Q9Y622[Other Products]
UniProt Related Accession #
P12882[Other Products]
Molecular Weight
223,145 Da
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NCBI Official Full Name
myosin-1
NCBI Official Synonym Full Names
myosin heavy chain 1
NCBI Official Symbol
MYH1  [Similar Products]
NCBI Official Synonym Symbols
MYHa; HEL71; MYHSA1; MyHC-2x; MyHC-2X/D
  [Similar Products]
NCBI Protein Information
myosin-1
UniProt Protein Name
Myosin-1
UniProt Synonym Protein Names
Myosin heavy chain 1; Myosin heavy chain 2x; MyHC-2x; Myosin heavy chain IIx/d; MyHC-IIx/d; Myosin heavy chain, skeletal muscle, adult 1
Protein Family
Myosin
UniProt Gene Name
MYH1  [Similar Products]
UniProt Synonym Gene Names
MyHC-2x; MyHC-IIx/d  [Similar Products]
UniProt Entry Name
MYH1_HUMAN
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NCBI Summary for MYH1
Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development. [provided by RefSeq, Jul 2008]
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UniProt Comments for MYH1
MYH1: Muscle contraction.

Protein type: Motility/polarity/chemotaxis; Motor

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: muscle myosin complex

Molecular Function: protein binding
Research Articles on MYH1
1. Transcriptional levels of MHC-I, MHC-IIa, and MHC-IIb in denervation groups were significantly down-regulated compared with controls
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-MYH1 antibody
 Products by Pathway  Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
 Translocation Of GLUT4 To The Plasma Membrane Pathway antibodies  Translocation Of GLUT4 To The Plasma Membrane Pathway Diagram
 Vesicle-mediated Transport Pathway antibodies  Vesicle-mediated Transport Pathway Diagram
Diseases associated with anti-MYH1 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >2 publications with MYH1 and Breast Neoplasms
 Carcinoma Antibodies  >1 publications with MYH1 and Carcinoma
 Cardiovascular Diseases Antibodies  >1 publications with MYH1 and Cardiovascular Diseases
 Chromosome Aberrations Antibodies  >1 publications with MYH1 and Chromosome Aberrations
 Heart Diseases Antibodies  >1 publications with MYH1 and Heart Diseases
 Insulin Resistance Antibodies  >1 publications with MYH1 and Insulin Resistance
 Disease Models, Animal Antibodies  >1 publications with MYH1 and Disease Models, Animal
 Fibrosis Antibodies  >1 publications with MYH1 and Fibrosis
 Inflammation Antibodies  >1 publications with MYH1 and Inflammation
 Cardiomyopathies Antibodies  >1 publications with MYH1 and Cardiomyopathies
Organs/Tissues associated with anti-MYH1 antibody
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >39 publications with MYH1 and Muscle
 Bone Antibodies  >3 publications with MYH1 and Bone
 Testis Antibodies  >2 publications with MYH1 and Testis
 Heart Antibodies  >2 publications with MYH1 and Heart
 Mouth Antibodies  >1 publications with MYH1 and Mouth
 Uncharacterized Tissue Antibodies  >1 publications with MYH1 and Uncharacterized Tissue
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