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anti-NFkappaB-p100 antibody :: Rabbit NFkappaB-p100 Polyclonal Antibody

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Catalog # MBS2536361
Unit / Price
  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Western Blot (WB)
Product Name

NFkappaB-p100, Polyclonal Antibody

Popular Item
Also Known As

NFkappaB-p100 Polyclonal Antibody

Product Synonym Names
NFKB2; LYT10; Nuclear factor NF-kappa-B p100 subunit; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; Oncogene Lyt-10; Lyt10
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Antigen Affinity Purified
1 mg/ml (lot specific)
Synthesized peptide derived from human NFkappaB-p100 around the non-phosphorylation site of S865.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-NFkappaB-p100 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-NFkappaB-p100 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-NFkappaB-p100 antibody
WB: 1:500-1:2000, IHC: 1:50-1:200, IP: 1:100, IF: 1:50-1:100, ELISA: 1:5000-1:20000

Western Blot (WB) of anti-NFkappaB-p100 antibody
Western Blot analysis of various cells using NF?B-p100 Polyclonal Antibody at dilution of 1:1000.
anti-NFkappaB-p100 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for NFkappaB-p100. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Calculated MW: 97
NCBI Official Full Name
nuclear factor NF-kappa-B p100 subunit isoform b
NCBI Official Synonym Full Names
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
NCBI Official Symbol
NFKB2  [Similar Products]
NCBI Official Synonym Symbols
p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100
  [Similar Products]
NCBI Protein Information
nuclear factor NF-kappa-B p100 subunit
UniProt Protein Name
Nuclear factor NF-kappa-B p100 subunit
UniProt Synonym Protein Names
DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; Oncogene Lyt-10; Lyt10
UniProt Gene Name
NFKB2  [Similar Products]
UniProt Synonym Gene Names
LYT10; Lyt10  [Similar Products]
UniProt Entry Name
NCBI Summary for NFkappaB-p100
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
UniProt Comments for NFkappaB-p100
NFkB-p100: a transcription factor of the nuclear factor-kappaB ( NFkB) group. Precursor of the p52 subunit of the nuclear factor NF-kappa-B, which binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. The precursor protein itself does not bind to DNA. LT-beta receptor agonists and LPS induce NF-kappaB/p100 processing to p52 at the level of the ribosome. There are five NFkB proteins in mammals (RelA/NFkB-p65, RelB, c-Rel, NF-_B1/NFkB-p105, and NF-_B2/NFkB-p100). They form a variety of homodimers and heterodimers, each of which activates its own characteristic set of genes. Two spliced isoforms have been identified. Isoform p49 is a subunit of the NF-kappa-B protein complex, which stimulates the HIV enhancer in synergy with p65.

Protein type: Transcription factor; Oncoprotein; DNA-binding

Chromosomal Location of Human Ortholog: 10q24

Cellular Component: Bcl3/NF-kappaB2 complex; cytoplasm; cytosol; nucleoplasm; nucleus

Molecular Function: chromatin binding; protein binding; transcription coactivator activity; transcription factor activity

Biological Process: activation of NF-kappaB transcription factor; aging; extracellular matrix organization and biogenesis; follicular dendritic cell differentiation; germinal center formation; I-kappaB kinase/NF-kappaB cascade; inflammatory response; innate immune response; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; positive regulation of interferon type I production; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; response to cytokine stimulus; response to lipopolysaccharide; rhythmic process; spleen development; stimulatory C-type lectin receptor signaling pathway; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 5 signaling pathway; toll-like receptor 9 signaling pathway; toll-like receptor signaling pathway; transcription from RNA polymerase II promoter; tumor necrosis factor-mediated signaling pathway

Disease: Immunodeficiency, Common Variable, 10
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