AAH01283.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Nuclear factor I/B
NCBI Official Synonym Full Names
nuclear factor I/B
NCBI Official Synonym Symbols
CTF; NF1-B; NFI-B; NFIB2; NFIB3; NF-I/B; NFI-RED; HMGIC/NFIB [Similar Products]
NCBI Protein Information
nuclear factor 1 B-type; nuclear factor 1/B; TGGCA-binding protein; CCAAT-box-binding transcription factor
UniProt Protein Name
Nuclear factor 1 B-type
UniProt Synonym Protein Names
CCAAT-box-binding transcription factor; CTF; Nuclear factor I/B; NF-I/B; NFI-B; TGGCA-binding protein
UniProt Synonym Gene Names
UniProt Entry Name
NFIB_HUMAN
UniProt Comments for NFIB
NFI-B: Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 9p24.1
Cellular Component: nucleoplasm; nucleolus; nucleus
Molecular Function: DNA binding; double-stranded DNA binding
Biological Process: transcription from RNA polymerase II promoter; pontine nucleus development; glial cell differentiation; anterior commissure morphogenesis; chondrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; DNA replication; negative regulation of DNA binding; hindbrain development
Research Articles on NFIB
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Products associated with anti-NFIB antibody
Pathways associated with anti-NFIB antibody
Diseases associated with anti-NFIB antibody
Disease Name |
Pubmed Publications |
Adenocarcinoma Antibodies |
>33 publications with NFIB and Adenocarcinoma |
Carcinoma, Adenoid Cystic Antibodies |
>33 publications with NFIB and Carcinoma, Adenoid Cystic |
Breast Neoplasms Antibodies |
>14 publications with NFIB and Breast Neoplasms |
Neoplasms, Experimental Antibodies |
>5 publications with NFIB and Neoplasms, Experimental |
Nervous System Diseases Antibodies |
>5 publications with NFIB and Nervous System Diseases |
Brain Diseases Antibodies |
>3 publications with NFIB and Brain Diseases |
Carcinoma, Squamous Cell Antibodies |
>3 publications with NFIB and Carcinoma, Squamous Cell |
Cell Transformation, Neoplastic Antibodies |
>3 publications with NFIB and Cell Transformation, Neoplastic |
Lung Neoplasms Antibodies |
>3 publications with NFIB and Lung Neoplasms |
Abnormalities, Drug-Induced Antibodies |
>1 publications with NFIB and Abnormalities, Drug-Induced |
Organs/Tissues associated with anti-NFIB antibody
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