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anti-NUF2 antibody :: Rabbit NUF2, NDC80 kinetochore complex component, homolog Polyclonal Antibody

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Catalog # MBS714241
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-NUF2 antibody
Product Name

NUF2, NDC80 kinetochore complex component, homolog, Polyclonal Antibody

Full Product Name

Rabbit anti-human NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) polyclonal Antibody

Product Synonym Names
NUF2; NDC80 kinetochore complex component; homolog (S. cerevisiae); NUF2; CDCA1; NUF2R
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
611772
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human NUF2
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-103429 / sc-98369
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-NUF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-NUF2 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for NUF2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,304 Da[Similar Products]
NCBI Official Full Name
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
NCBI Official Synonym Full Names
NUF2, NDC80 kinetochore complex component
NCBI Official Symbol
NCBI Official Synonym Symbols
CDCA1; CT106; NUF2R
  [Similar Products]
NCBI Protein Information
kinetochore protein Nuf2; hNuf2; hNuf2R; hsNuf2; cancer/testis antigen 106; cell division cycle associated 1; cell division cycle-associated protein 1; NUF2, NDC80 kinetochore complex component, homolog
UniProt Protein Name
Kinetochore protein Nuf2
UniProt Synonym Protein Names
Cell division cycle-associated protein 1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
CDCA1; NUF2R; hNuf2; hNuf2R; hsNuf2  [Similar Products]
UniProt Entry Name
NUF2_HUMAN
NCBI Summary for NUF2
This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for NUF2
NUF2: Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. Belongs to the NUF2 family.

Protein type: DNA replication; Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: membrane; nucleus; cytosol; chromosome, pericentric region

Molecular Function: protein binding

Biological Process: mitosis; cell division; mitotic cell cycle; chromosome segregation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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