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anti-P2RY1 antibody :: Rabbit P2RY1 Polyclonal Antibody

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Catalog # MBS9414776
Unit / Price
  0.1 mL  /  $255 +1 FREE 8GB USB
Product Name

P2RY1, Polyclonal Antibody

Popular Item
Also Known As

P2RY1 Antibody

Product Synonym Names
P2Y1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
373
OMIM
601167
3D Structure
ModBase 3D Structure for P47900
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
The antibody detects endogenous levels of total P2RY1 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
2.8 mg/ml (lot specific)
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to a region derived from internal residues of human purinergic receptor P2Y, G-protein coupled, 1
Target Name
P2RY1
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-P2RY1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-P2RY1 antibody
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
Product Categories/Family for anti-P2RY1 antibody
Applications Tested/Suitable for anti-P2RY1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-P2RY1 antibody
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200

Testing Data of anti-P2RY1 antibody
Gel: 10%SDS-PAGE Lysates (from left to right): A549 cell and mouse liver tissue Amount of lysate: 40ug per lane Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 30 seconds
anti-P2RY1 antibody Testing Data image
Immunohistochemistry (IHC) of anti-P2RY1 antibody
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/40.
anti-P2RY1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for P2RY1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
42kD
NCBI Official Full Name
P2Y purinoceptor 1
NCBI Official Synonym Full Names
purinergic receptor P2Y, G-protein coupled, 1
NCBI Official Symbol
P2RY1  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
P2Y purinoceptor 1
UniProt Protein Name
P2Y purinoceptor 1
UniProt Synonym Protein Names
ATP receptor; Purinergic receptor
Protein Family
UniProt Gene Name
P2RY1  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
P2RY1_HUMAN
NCBI Summary for P2RY1
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]
UniProt Comments for P2RY1
P2RY1: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1

Chromosomal Location of Human Ortholog: 3q25.2

Cellular Component: postsynaptic membrane; cell surface; mitochondrion; integral to plasma membrane; basolateral plasma membrane; dendrite; apical plasma membrane; plasma membrane

Molecular Function: ATP-activated nucleotide receptor activity; protein binding; purinergic nucleotide receptor activity, G-protein coupled; protein heterodimerization activity; receptor activity; A1 adenosine receptor binding; ADP binding; ATP binding; ADP-activated nucleotide receptor activity

Biological Process: platelet activation; regulation of vasodilation; eating behavior; positive regulation of hormone secretion; positive regulation of inositol trisphosphate biosynthetic process; sensory perception of pain; negative regulation of binding; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; response to mechanical stimulus; positive regulation of transcription from RNA polymerase II promoter; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of ion transport; positive regulation of protein amino acid phosphorylation; regulation of receptor activity; G-protein signaling, adenylate cyclase inhibiting pathway; blood coagulation; adenosine receptor signaling pathway; aging
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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