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anti-PARG antibody :: Rabbit PARG Polyclonal Antibody

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Catalog # MBS9131066
Unit / Price
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  0.05 mL  /  $200 +1 FREE 8GB USB
  0.1 mL  /  $275 +1 FREE 8GB USB
  0.2 mL  /  $430 +1 FREE 8GB USB
Product Name

PARG, Polyclonal Antibody

Popular Item
Full Product Name

PARG Polyclonal Antibody

Product Synonym Names
PARG; PARG99; poly(ADP-ribose) glycohydrolase
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
AY258587 mRNA
3D Structure
ModBase 3D Structure for Q86W56
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 777-976 of human PARG (NP_003622.2).
Calculated MW
54kDa/60kDa/99kDa/102kDa/111kDa
Observed MW
111kDa
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20°C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-PARG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PARG antibody
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-PARG antibody
Applications Tested/Suitable for anti-PARG antibody
Western Blot (WB)
Application Notes for anti-PARG antibody
WB: 1:1000 - 1:2000

Western Blot (WB) of anti-PARG antibody
Western blot analysis of extracts of various cell lines, using PARG antibody at 1:7000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 20s.
anti-PARG antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-PARG antibody
Western Blot analysis of extract various cells, using PARG antibody (MBS9131066) at 1:1000 dilution ratio through one-step method.
Secondary antibody: HRP Goat Anti-Rabbit
IgG (H+L) (MBS128200) at 1:4000 dilution.
Lysates/ proteins : 25 ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.
anti-PARG antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for PARG. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Poly(ADP-ribose) glycohydrolase
NCBI Official Synonym Full Names
poly(ADP-ribose) glycohydrolase
NCBI Official Symbol
NCBI Official Synonym Symbols
PARG99
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NCBI Protein Information
poly(ADP-ribose) glycohydrolase
UniProt Protein Name
Poly(ADP-ribose) glycohydrolase
UniProt Gene Name
NCBI Summary for PARG
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
UniProt Comments for PARG
PARG: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Belongs to the poly(ADP-ribose) glycohydrolase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.2.1.143; Hydrolase

Chromosomal Location of Human Ortholog: 10q11.23

Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; nucleoplasm; nucleus

Molecular Function: poly(ADP-ribose) glycohydrolase activity; protein binding
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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