• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-PEPD antibody :: Rabbit PEPD Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS9408303
Unit / Price
Scan QR to view Datasheet
  0.1 mL  /  $255 +1 FREE 8GB USB
Western Blot (WB)
Product Name

PEPD, Polyclonal Antibody

Popular Item
Full Product Name

PEPD Antibody

Product Synonym Names
PROLIDASE
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
170100
3D Structure
ModBase 3D Structure for P12955
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
The antibody detects endogenous level of total PEPD protein.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (lot specific)
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human PEPD.
Target Name
PEPD
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-PEPD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PEPD antibody
This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-PEPD antibody
Applications Tested/Suitable for anti-PEPD antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PEPD antibody
Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:200

Western Blot (WB) of anti-PEPD antibody
Western blot analysis of extracts of various cell lines, using PEPD antibody.
anti-PEPD antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for PEPD. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54kD
NCBI Official Full Name
xaa-Pro dipeptidase isoform 1
NCBI Official Synonym Full Names
peptidase D
NCBI Official Symbol
NCBI Official Synonym Symbols
PROLIDASE
  [Similar Products]
NCBI Protein Information
xaa-Pro dipeptidase
UniProt Protein Name
Xaa-Pro dipeptidase
UniProt Synonym Protein Names
Imidodipeptidase; Peptidase D; Proline dipeptidase; Prolidase
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
PRD; X-Pro dipeptidase; Prolidase  [Similar Products]
UniProt Entry Name
PEPD_HUMAN
NCBI Summary for PEPD
This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
UniProt Comments for PEPD
peptidase D: Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position. Plays an important role in collagen metabolism because the high level of iminoacids in collagen. Defects in PEPD are a cause of prolidase deficiency (PD). Prolidase deficiency is an autosomal recessive disorder associated with iminodipeptiduria. The clinical phenotype includes skin ulcers, mental retardation, recurrent infections, and a characteristic facies. These features, however are incompletely penetrant and highly variable in both age of onset and severity. There is a tight linkage between the polymorphisms of prolidase and the myotonic dystrophy trait. Belongs to the peptidase M24B family. Eukaryotic-type prolidase subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; EC 3.4.13.9

Chromosomal Location of Human Ortholog: 19q13.11

Molecular Function: dipeptidase activity; manganese ion binding; aminopeptidase activity; metallocarboxypeptidase activity

Biological Process: amino acid metabolic process; collagen catabolic process; proteolysis

Disease: Prolidase Deficiency
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000