• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-PIK3R6 antibody :: Rabbit PIK3R6 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS820596
Unit / Price
Scan QR to view Datasheet
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
anti-PIK3R6 antibody
Product Name

PIK3R6, Polyclonal Antibody

Popular Item
Full Product Name

Anti-PIK3R6 Antibody

Product Synonym Names
C17orf38; Phosphoinositide 3-kinase regulatory subunit 6; Phosphoinositide 3-kinase gamma adapter protein of 87 kDa; p84 PI3K adapter protein; p84 PIKAP; p87 PI3K adapter protein; p87PIKAP
Antibody/Peptide Pairs
PIK3R6 peptide (MBS822460) is used for blocking the activity of PIK3R6 antibody (MBS820596)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
611462
3D Structure
ModBase 3D Structure for Q5UE93
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of PIK3R6 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PIK3R6. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-PIK3R6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PIK3R6 antibody
Rabbit polyclonal antibody to PIK3R6
Applications Tested/Suitable for anti-PIK3R6 antibody
Western Blot (WB)
Application Notes for anti-PIK3R6 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-PIK3R6 antibody
anti-PIK3R6 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for PIK3R6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
84,258 Da
NCBI Official Full Name
phosphoinositide 3-kinase regulatory subunit 6 isoform 1
NCBI Official Synonym Full Names
phosphoinositide-3-kinase, regulatory subunit 6
NCBI Official Symbol
PIK3R6  [Similar Products]
NCBI Official Synonym Symbols
C17orf38; HsT41028; p87PIKAP; p84 PIKAP; p87(PIKAP)
  [Similar Products]
NCBI Protein Information
phosphoinositide 3-kinase regulatory subunit 6; p84 PI3K adapter protein; PI3Kgamma adapter protein of 87 kDa; p87 phosphoinositide 3-kinase gamma (PI3Kg) adapter protein
UniProt Protein Name
Phosphoinositide 3-kinase regulatory subunit 6
UniProt Synonym Protein Names
Phosphoinositide 3-kinase gamma adapter protein of 87 kDa; p84 PI3K adapter protein; p84 PIKAP; p87 PI3K adapter protein; p87PIKAP
UniProt Gene Name
PIK3R6  [Similar Products]
UniProt Synonym Gene Names
C17orf38; p84 PIKAP; p87PIKAP  [Similar Products]
UniProt Entry Name
PI3R6_HUMAN
NCBI Summary for PIK3R6
Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
UniProt Comments for PIK3R6
PIK3R6: Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS1 bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis; signaling seems to involve RRAS.

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: membrane; cytosol

Molecular Function: protein binding; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; 1-phosphatidylinositol-3-kinase regulator activity

Biological Process: positive regulation of MAP kinase activity; G-protein coupled receptor protein signaling pathway; platelet activation; positive regulation of angiogenesis; phosphoinositide phosphorylation; phospholipid metabolic process; phosphatidylinositol biosynthetic process; angiogenesis; blood coagulation; regulation of phosphoinositide 3-kinase activity
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000