BAA13468.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
platelet-activating factor acetylhydrolase 2
NCBI Official Synonym Full Names
platelet-activating factor acetylhydrolase 2, 40kDa
NCBI Official Synonym Symbols
NCBI Protein Information
platelet-activating factor acetylhydrolase 2, cytoplasmic; SD-PLA2; serine-dependent phospholipase A2
UniProt Protein Name
Platelet-activating factor acetylhydrolase 2, cytoplasmic
UniProt Synonym Protein Names
Serine-dependent phospholipase A2; SD-PLA2; hSD-PLA2
UniProt Synonym Gene Names
UniProt Entry Name
PAFA2_HUMAN
NCBI Summary for PAFAH2
This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme. [provided by RefSeq, Jul 2008]
UniProt Comments for PAFAH2
PAFAH2: Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme. Belongs to the serine esterase family.
Protein type: Lipid-binding; Hydrolase; Lipid Metabolism - ether lipid; EC 3.1.1.47
Chromosomal Location of Human Ortholog: 1p36
Cellular Component: cytoplasm
Molecular Function: phospholipid binding; 1-alkyl-2-acetylglycerophosphocholine esterase activity
Biological Process: lipid metabolic process; lipid catabolic process; negative regulation of apoptosis
Research Articles on PAFAH2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-PAFAH2 antibody
Diseases associated with anti-PAFAH2 antibody
Organs/Tissues associated with anti-PAFAH2 antibody
| 
ELISA Kit
CLIA Kit
PCR Kit
Monoclonal Antibody
Polyclonal Antibody
Secondary Antibody
Antigen
Biochemical
cDNA Clone
siRNA
Peptide
Rec./Purified Protein
Custom ELISA Kit
Custom Protein
Custom Antibody
Antibody Matched Pairs
Antibody Peptide Pairs
Phospho Antibodies
Products by Disease
Products by Pathway
Products by Tissue