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anti-PTPN18 antibody :: Rabbit PTPN18 Polyclonal Antibody

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Catalog # MBS7603167
Unit / Price
  0.1 mg  /  $265 +1 FREE 8GB USB
Product Name

PTPN18, Polyclonal Antibody

Popular Item
Also Known As

PTPN18 Rabbit Polyclonal

Product Synonym Names
BDPl, Brain derived phosphatase, PTP HSCF, PTPN18
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
3D Structure
ModBase 3D Structure for Q99952
Species Reactivity
Human, Mouse,Rat; other species are not tested. Please decide the specificity by homology
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-PTPN18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PTPN18 antibody
PTPNI8(Tyrosine-protein phosphatase non-receptor type 18) is also named as BDP 1 and belongs to the protein-tyrosine phosphatase family. The PTPN18 cDNA encodes a deduced 459-amino acid protein with no transmembrane domain and a calculated molecular weight of 50 kD. PTPN18 has a PEST motif and shares the greatest homology with members of the PTP-PEST gene family. Northern blot analysis indicated that PTPN 18 is expressed not only in brain, but also in colon and several different tumor-derived cell lines.(PMID:8950995). It has 2 isoforms produced by alternative splicing.
Applications Tested/Suitable for anti-PTPN18 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PTPN18 antibody
WB: 1:500-1:5000
IHC: 1:20-1:200

Immunohistochemical of anti-PTPN18 antibody
Immunohistochemical of paraffin-embedded human brain using MBS7603167(PTPN18 antibody) at dilution of 1: 100
anti-PTPN18 antibody Immunohistochemical image
human brain tissue were subjected to SDS PAGE followed by western blot with MBS7603167(PTPN18 antibody) at dilution of 1:500
anti-PTPN18 antibody SDS-PAGE image
NCBI/Uniprot data below describe general gene information for PTPN18. It may not necessarily be applicable to this product.
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
NCBI Official Full Name
PTPN18 protein
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 18
NCBI Official Symbol
PTPN18  [Similar Products]
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 18
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 18
UniProt Synonym Protein Names
Brain-derived phosphatase
UniProt Gene Name
PTPN18  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
NCBI Summary for PTPN18
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
UniProt Comments for PTPN18
BDP1: a member of the non-receptor protein tyrosine phosphatase (PTP) family. Contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This gene was found to be expressed in brain, colon tissues, and several different tumor-derived cell lines.

Protein type: Motility/polarity/chemotaxis; Protein phosphatase, tyrosine (non-receptor); EC

Chromosomal Location of Human Ortholog: 2q21.1

Cellular Component: cytoplasm; nucleus

Molecular Function: non-membrane spanning protein tyrosine phosphatase activity; protein binding

Biological Process: protein amino acid dephosphorylation
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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Pathways associated with anti-PTPN18 antibody
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