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anti-PPFIBP1 antibody :: Rabbit PTPRF interacting protein, binding protein 1 Polyclonal Antibody

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Catalog # MBS714607
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-PPFIBP1 antibody
Product Name

PTPRF interacting protein, binding protein 1 (PPFIBP1), Polyclonal Antibody

Full Product Name

Rabbit anti-human PTPRF interacting protein, binding protein 1 (liprin beta 1) polyclonal Antibody

Product Synonym Names
PTPRF interacting protein; binding protein 1 (liprin beta 1); PPFIBP1; L2; hSGT2; hSgt2p
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
603141
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human PPFIBP1
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22876
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-PPFIBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PPFIBP1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for PPFIBP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,972 Da[Similar Products]
NCBI Official Full Name
PTPRF interacting protein, binding protein 1 (liprin beta 1), isoform CRA_a
NCBI Official Synonym Full Names
PTPRF interacting protein, binding protein 1 (liprin beta 1)
NCBI Official Symbol
PPFIBP1  [Similar Products]
NCBI Official Synonym Symbols
L2; SGT2; hSGT2; hSgt2p
  [Similar Products]
NCBI Protein Information
liprin-beta-1; liprin-beta 1; liprin related protein; PTPRF-interacting protein-binding protein 1; protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; protein-tyrosine phosphatase receptor-type f polypeptide-interacting protein-binding protein 1
UniProt Protein Name
Liprin-beta-1
UniProt Synonym Protein Names
Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; PTPRF-interacting protein-binding protein 1; hSGT2
Protein Family
UniProt Gene Name
PPFIBP1  [Similar Products]
UniProt Synonym Gene Names
KIAA1230; PTPRF-interacting protein-binding protein 1  [Similar Products]
UniProt Entry Name
LIPB1_HUMAN
NCBI Summary for PPFIBP1
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
UniProt Comments for PPFIBP1
liprin beta 1: a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Five alternatively spliced isoforms have been described.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 12p12.1

Cellular Component: focal adhesion; plasma membrane

Biological Process: cell adhesion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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