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anti-PUMA antibody :: Rabbit PUMA Polyclonal Antibody

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Catalog # MBS2535179
Unit / Price
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  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Western Blot (WB)
Product Name

PUMA, Polyclonal Antibody

Popular Item
Full Product Name

PUMA Polyclonal Antibody

Product Synonym Names
BBC3; PUMA; Bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Concentration
1 mg/ml (lot specific)
Immunogen
Synthesized peptide derived from the C-terminal region of human PUMA.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-PUMA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-PUMA antibody
Applications Tested/Suitable for anti-PUMA antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-PUMA antibody
WB: 1:500-1:2000, ELISA: 1:5000-1:20000

Western Blot (WB) of anti-PUMA antibody
Western Blot analysis of various cells with PUMA Polyclonal Antibody.
anti-PUMA antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for PUMA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
Molecular Weight
Observed MW: 23
NCBI Official Full Name
PUMA
NCBI Official Synonym Full Names
Bcl-2 binding component 3
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
bcl-2-binding component 3
UniProt Protein Name
Bcl-2-binding component 3
UniProt Synonym Protein Names
p53 up-regulated modulator of apoptosis
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
BBC3_RAT
UniProt Comments for PUMA
PUMA: Essential mediator of p53/TP53-dependent and p53/TP53- independent apoptosis. Interacts with MCL1 and BCL2A1. Interacts with BCL2 and BCL2L1/BCL-XL. By DNA damage, glucocorticoid treatment, growth factor deprivation and p53/TP53. Ubiquitously expressed. Belongs to the Bcl-2 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial

Cellular Component: endoplasmic reticulum; lysosome; mitochondrion

Molecular Function: ATPase binding; glycoprotein binding; protein binding

Biological Process: apoptosis; brain development; caspase activation; determination of adult life span; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; glial cell differentiation; negative regulation of growth; positive regulation of apoptosis; positive regulation of neuron apoptosis; positive regulation of protein homooligomerization; reduction of endoplasmic reticulum calcium ion concentration; release of cytochrome c from mitochondria; release of sequestered calcium ion into cytosol; response to DNA damage stimulus
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-PUMA antibody
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