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Add To Compare List anti-RAB3A antibody :: Rabbit RAB3A Polyclonal Antibody Catalog # MBS9603689 Unit / Price 0.1 mL / $270 +1 FREE 8GB USB 0.2 mL / $315 +1 FREE 8GB USB 5x0.2 mL / $1,245 +1 FREE 8GB USB Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name RAB3A, Polyclonal Antibody Popular Item Full Product Name RAB3A Antibody Product Synonym Names Rab 3A; RAB 3A member RAS oncogene family; Rab3a; RAB3A member RAS oncogene family; RAB3A_HUMAN; RAS associated protein RAB 3A; RAS associated protein RAB3A; Ras related protein Rab 3A; Ras related protein Rab3A; Ras-related protein Rab-3A Product Gene Name anti-RAB3A antibody[Similar Products] Antibody/Peptide Pairs Rab3A peptide (MBS9621166) is used for blocking the activity of Rab3A antibody (MBS9603689) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP 3D Structure ModBase 3D Structure for P20336 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human, Mouse, Rat Specificity RAB3A antibody detects endogenous levels of RAB3A. Purity/Purification The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin. Form/Format LiquidPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Concentration 1mg/ml (lot specific) Immunogen A synthesized peptide derived from human RAB3A. Subcellular Location Cell Membrane Tissue Specificity Specifically expressed in brain. Predicted Cross Reactivity Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus Similarity Pig (100%), Bovine (93%), Horse (100%), Sheep (93%), Dog (100%), Chicken (100%), Xenopus (100%) Conjugation Unconjugated Preparation and Storage Store at -20 degree C. Stable for 12 months from date of receipt. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Supply Chain Verification Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire. Other Notes Small volumes of anti-RAB3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-RAB3A antibody Function: Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.Subunit Structure: Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A and RPH3AL. Interacts with the exocyst complex through SEC15. Binds SYTL4 and RIMS1. Interacts with RAB3IP. Interacts with SGSM1 and SGSM3 (By similarity).Similarity: Belongs to the small GTPase superfamily. Rab family. Applications Tested/Suitable for anti-RAB3A antibody Western Blot (WB), Immunohistochemistry (IHC) Application Notes for anti-RAB3A antibody WB: 1:500-1:2000IHC: 1:50-1:200 Immunohistochemistry (IHC) of anti-RAB3A antibody MBS9603689 at 1/100 staining Human thyroid cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western Blot (WB) of anti-RAB3A antibody Western blot analysis of extracts of mouse brain tissue, using RAB3A antibody. TOP NCBI/Uniprot data below describe general gene information for RAB3A. It may not necessarily be applicable to this product. NCBI GI # 4506367 NCBI GeneID 5864 NCBI Accession # NP_002857.1 [Other Products] NCBI GenBank Nucleotide # NM_002866.4 [Other Products] UniProt Primary Accession # P20336 [Other Products] UniProt Secondary Accession # Q9NYE1; A8K0J4[Other Products] UniProt Related Accession # P20336[Other Products] Molecular Weight Observed: 25 kDaPredicted: 25 kDa TOP NCBI Official Full Name ras-related protein Rab-3A NCBI Official Synonym Full Names RAB3A, member RAS oncogene family NCBI Official Symbol RAB3A [Similar Products] NCBI Protein Information ras-related protein Rab-3A UniProt Protein Name Ras-related protein Rab-3A Protein Family Ras-related protein UniProt Gene Name RAB3A [Similar Products] TOP TOP UniProt Comments for RAB3A Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. Research Articles on RAB3A 1. Rab3A-22A blocks exocytosis at a stage downstream intra-acrosomal calcium release. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-RAB3A antibody Reference Product PubMed Publications RIMS1 antibody >18 publications with RAB3A and RIMS1 VAMP2 antibody >13 publications with RAB3A and VAMP2 RPH3AL antibody >12 publications with RAB3A and RPH3AL SYT1 antibody >10 publications with RAB3A and SYT1 SYTL4 antibody >7 publications with RAB3A and SYTL4 UNC13B antibody >3 publications with RAB3A and UNC13B RPH3A antibody >1 publications with RAB3A and RPH3A Pathways associated with anti-RAB3A antibody Products by Pathway Pathway Diagram Acetylcholine Neurotransmitter Release Cycle Pathway antibodies Acetylcholine Neurotransmitter Release Cycle Pathway Diagram BDNF Signaling Pathway antibodies BDNF Signaling Pathway Diagram Dopamine Neurotransmitter Release Cycle Pathway antibodies Dopamine Neurotransmitter Release Cycle Pathway Diagram GABA Synthesis, Release, Reuptake And Degradation Pathway antibodies GABA Synthesis, Release, Reuptake And Degradation Pathway Diagram Glutamate Neurotransmitter Release Cycle Pathway antibodies Glutamate Neurotransmitter Release Cycle Pathway Diagram Insulin Secretion Pathway antibodies Insulin Secretion Pathway Diagram Neuronal System Pathway antibodies Neuronal System Pathway Diagram Neurotransmitter Release Cycle Pathway antibodies Neurotransmitter Release Cycle Pathway Diagram Norepinephrine Neurotransmitter Release Cycle Pathway antibodies Norepinephrine Neurotransmitter Release Cycle Pathway Diagram Serotonin Neurotransmitter Release Cycle Pathway antibodies Serotonin Neurotransmitter Release Cycle Pathway Diagram Diseases associated with anti-RAB3A antibody Disease Name Pubmed Publications Nervous System Diseases Antibodies >43 publications with RAB3A and Nervous System Diseases Brain Diseases Antibodies >29 publications with RAB3A and Brain Diseases Neurodegenerative Diseases Antibodies >20 publications with RAB3A and Neurodegenerative Diseases Disease Models, Animal Antibodies >7 publications with RAB3A and Disease Models, Animal Movement Disorders Antibodies >6 publications with RAB3A and Movement Disorders Nerve Degeneration Antibodies >6 publications with RAB3A and Nerve Degeneration Kidney Diseases Antibodies >5 publications with RAB3A and Kidney Diseases Neurobehavioral Manifestations Antibodies >5 publications with RAB3A and Neurobehavioral Manifestations Atrophy Antibodies >4 publications with RAB3A and Atrophy Immune System Diseases Antibodies >3 publications with RAB3A and Immune System Diseases Organs/Tissues associated with anti-RAB3A antibody Organ/Tissue Name Pubmed Publications Nerve Antibodies >241 publications with RAB3A and Nerve Brain Antibodies >232 publications with RAB3A and Brain Embryonic Tissue Antibodies >19 publications with RAB3A and Embryonic Tissue Lung Antibodies >11 publications with RAB3A and Lung Eye Antibodies >6 publications with RAB3A and Eye Testis Antibodies >5 publications with RAB3A and Testis Bone Antibodies >3 publications with RAB3A and Bone Ovary Antibodies >3 publications with RAB3A and Ovary Intestine Antibodies >2 publications with RAB3A and Intestine Mammary Gland Antibodies >2 publications with RAB3A and Mammary Gland TOP © 2006-24 MyBioSource.com. 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