NP_036381.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 25 kDa Predicted: 23 kDa
NCBI Official Full Name
rho-related GTP-binding protein RhoQ
NCBI Official Synonym Full Names
ras homolog family member Q
NCBI Official Synonym Symbols
ARHQ; TC10; TC10A; RASL7A; HEL-S-42 [Similar Products]
NCBI Protein Information
rho-related GTP-binding protein RhoQ
UniProt Protein Name
Rho-related GTP-binding protein RhoQ
UniProt Synonym Protein Names
Ras-like protein TC10; Ras-like protein family member 7A
UniProt Synonym Gene Names
NCBI Summary for RHOQ
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011]
UniProt Comments for RHOQ
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
Research Articles on RHOQ
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Products associated with anti-RHOQ antibody
Pathways associated with anti-RHOQ antibody
Diseases associated with anti-RHOQ antibody
Organs/Tissues associated with anti-RHOQ antibody
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