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anti-AHCYL1 antibody :: Rabbit S-adenosylhomocysteine hydrolase-like 1 Polyclonal Antibody

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Catalog # MBS710923
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-AHCYL1 antibody
Product Name

S-adenosylhomocysteine hydrolase-like 1 (AHCYL1), Polyclonal Antibody

Also Known As

Rabbit anti-human S-adenosylhomocysteine hydrolase-like 1 polyclonal Antibody

Product Synonym Names
S-adenosylhomocysteine hydrolase-like 1; AHCYL1; DCAL; IRBIT; PRO0233; XPVKONA
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
483
OMIM
607826
3D Structure
ModBase 3D Structure for O43865
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human AHCYL1
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162507
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-AHCYL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-AHCYL1 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for AHCYL1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,753 Da[Similar Products]
NCBI Official Full Name
S-adenosylhomocysteine hydrolase-like 1
NCBI Official Synonym Full Names
adenosylhomocysteinase-like 1
NCBI Official Symbol
AHCYL1  [Similar Products]
NCBI Official Synonym Symbols
DCAL; IRBIT; PPP1R78; PRO0233; XPVKONA
  [Similar Products]
NCBI Protein Information
putative adenosylhomocysteinase 2; adoHcyase 2; DC-expressed AHCY-like molecule; S-adenosyl-L-homocysteine hydrolase 2; S-adenosyl homocysteine hydrolase homolog; dendritic cell expressed AHCY-like protein; protein phosphatase 1, regulatory subunit 78; S-adenosylhomocysteine hydrolase-like protein 1; inositol 1,4,5-trisphosphate receptor-binding protein
UniProt Protein Name
Putative adenosylhomocysteinase 2
UniProt Synonym Protein Names
DC-expressed AHCY-like molecule; S-adenosyl-L-homocysteine hydrolase 2; S-adenosylhomocysteine hydrolase-like protein 1
Protein Family
UniProt Gene Name
AHCYL1  [Similar Products]
UniProt Synonym Gene Names
DCAL; XPVKONA; AdoHcyase 2  [Similar Products]
UniProt Entry Name
SAHH2_HUMAN
NCBI Summary for AHCYL1
The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
UniProt Comments for AHCYL1
AHCYL1: an inositol 1,4,5-trisphosphate receptor 1 (IP3R1)-binding protein that inhibits IP3 binding to IP3R1 and IP3-induced intracellular Ca2 release. Suppresses the activation of IP3R1 via a phosphorylation-dependent mechanism. Also binds the Na/HCO3 cotransporter 1 (SLC4A4) and may play an important role in pH regulation. Contains a domain homologous to S-adenosylhomocysteine hydrolase (SAHH), although it is reported to possess no hydrolase activity. Its expression is induced in cultured monocytes when they are differentiated into dendritic cells (DC) by exposure to GM-CSF and IL-4.

Protein type: Amino Acid Metabolism - cysteine and methionine; Hydrolase; EC 3.3.1.1; Other Amino Acids Metabolism - selenoamino acid

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: endoplasmic reticulum; cytosol

Molecular Function: protein binding; adenosylhomocysteinase activity

Biological Process: S-adenosylmethionine cycle; regulation of ion transmembrane transporter activity; mRNA polyadenylation; one-carbon compound metabolic process; protein export from nucleus; regulation of mRNA 3'-end processing
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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