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anti-SERPINB6 antibody :: Rabbit serpin peptidase inhibitor, clade B (ovalbumin), member 6 Polyclonal Antibody

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Catalog # MBS712162
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-SERPINB6 antibody
Product Name

serpin peptidase inhibitor, clade B (ovalbumin), member 6 (SERPINB6), Polyclonal Antibody

Full Product Name

Rabbit anti-human serpin peptidase inhibitor, clade B (ovalbumin), member 6 polyclonal Antibody

Product Synonym Names
serpin peptidase inhibitor; clade B (ovalbumin); member 6; SERPINB6; CAP; DKFZp686I04222; MGC111370; MSTP057; PI6; PTI; SPI3
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
gene 613453
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human SERPINB6
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21135 / sc-21143 / sc-292536
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-SERPINB6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SERPINB6 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for SERPINB6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,622 Da[Similar Products]
NCBI Official Full Name
serpin peptidase inhibitor, clade B (ovalbumin), member 6, isoform CRA_f
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade B (ovalbumin), member 6
NCBI Official Symbol
SERPINB6  [Similar Products]
NCBI Official Synonym Symbols
CAP; PI6; PTI; PI-6; SPI3; DFNB91; MSTP057
  [Similar Products]
NCBI Protein Information
serpin B6; cytoplasmic antiproteinase; protease inhibitor 6 (placental thrombin inhibitor); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6
UniProt Protein Name
Serpin B6
UniProt Synonym Protein Names
Cytoplasmic antiproteinase; CAP; Peptidase inhibitor 6; PI-6; Placental thrombin inhibitor
Protein Family
UniProt Gene Name
SERPINB6  [Similar Products]
UniProt Synonym Gene Names
PI6; PTI; CAP; PI-6  [Similar Products]
UniProt Entry Name
SPB6_HUMAN
NCBI Summary for SERPINB6
The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]
UniProt Comments for SERPINB6
SERPINB6: May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. Defects in SERPINB6 are the cause of deafness autosomal recessive type 91 (DFNB91). It is a form of non- syndromic deafness characterized by progressive and age-dependent sensorineural hearing loss. Vestibular function is normal. Belongs to the serpin family. Ov-serpin subfamily.

Chromosomal Location of Human Ortholog: 6p25

Cellular Component: extracellular space; protein complex; cytoplasm; cytosol; nucleus

Molecular Function: serine-type endopeptidase inhibitor activity; protease binding

Biological Process: sensory perception of sound

Disease: Deafness, Autosomal Recessive 91
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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