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anti-SLC5A2 antibody :: SGLT2 Polyclonal Antibody

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Catalog # MBS821113
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Western Blot (WB)
Product Name

SGLT2 (SLC5A2), Polyclonal Antibody

Popular Item
Full Product Name

Anti-SGLT2 Antibody

Product Synonym Names
SGLT2; Sodium/glucose cotransporter 2; Na(+)/glucose cotransporter 2; Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2
Antibody/Peptide Pairs
SGLT2 peptide (MBS823010) is used for blocking the activity of SGLT2 antibody (MBS821113)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
gene 233100
3D Structure
ModBase 3D Structure for P31639
Clonality
Polyclonal
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of SGLT2 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Source
Rabbit
Entrez Gene
6524 (Human); 246787 (Mouse); 64522 (Rat)
SwissProt
P31639 (Human); Q923I7 (Mouse); P53792 (Rat)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SGLT2. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-SLC5A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC5A2 antibody
Rabbit polyclonal antibody to SGLT2
Applications Tested/Suitable for anti-SLC5A2 antibody
Western Blot (WB)
Application Notes for anti-SLC5A2 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-SLC5A2 antibody
Western blot analysis of SGLT2 expression in HeLa (A), SP2/0 (B), H9C2 (C) whole cell lysates.
anti-SLC5A2 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for SLC5A2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
sodium/glucose cotransporter 2
NCBI Official Synonym Full Names
solute carrier family 5 (sodium/glucose cotransporter), member 2
NCBI Official Symbol
SLC5A2  [Similar Products]
NCBI Official Synonym Symbols
SGLT2
  [Similar Products]
NCBI Protein Information
sodium/glucose cotransporter 2; Na(+)/glucose cotransporter 2; solute carrier family 5 member 2; low affinity sodium-glucose cotransporter; solute carrier family 5 (sodium/glucose transporter), member 2
UniProt Protein Name
Sodium/glucose cotransporter 2
UniProt Synonym Protein Names
Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2
UniProt Gene Name
SLC5A2  [Similar Products]
UniProt Synonym Gene Names
SGLT2; Na(+)/glucose cotransporter 2  [Similar Products]
UniProt Entry Name
SC5A2_HUMAN
NCBI Summary for SLC5A2
This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. [provided by RefSeq, Sep 2009]
UniProt Comments for SLC5A2
SLC5A2: Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Defects in SLC5A2 are the cause of renal glucosuria (GLYS1). GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

Protein type: Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: plasma membrane; integral to membrane

Molecular Function: low-affinity glucose:sodium symporter activity

Biological Process: transport; carbohydrate metabolic process; sodium ion transport; glucose transport; transmembrane transport

Disease: Renal Glucosuria
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-SLC5A2 antibody
 Reference Product  PubMed Publications
 SLC2A2 antibody  >2 publications with SLC5A2 and SLC2A2
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