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anti-SGSM2 antibody :: Rabbit SGSM2 Polyclonal Antibody

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Catalog # MBS151080
Unit / Price
  0.1 mg  /  $375 +1 FREE 8GB USB
Product Name

SGSM2, Polyclonal Antibody

Popular Item
Also Known As

SGSM2 Antibody

Product Synonym Names
SGSM2; RUTBC1; KIAA0397; RUTBC1; Small G protein signaling modulator 2; RUN and TBC1 domain-containing protein 1; small G protein signaling modulator 2
Antibody/Peptide Pairs
SGSM2 peptide (MBS152368) is used for blocking the activity of SGSM2 antibody (MBS151080)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1051
OMIM
611418
3D Structure
ModBase 3D Structure for O43147
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
Multiple isoforms of SGSM2 are known to exist. SGSM2 antibody is predicted to not cross react with other SGSM family proteins.
Purity/Purification
SGSM2 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (lot specific)
Conjugate
Unconjugated
Immunogen
SGSM2 antibody was raised against an 18 amino acid synthetic peptide near the center of human SGSM2.
Buffer
SGSM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
SGSM2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Other Notes
Small volumes of anti-SGSM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SGSM2 antibody
SGSM2 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM2 is a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.
Applications Tested/Suitable for anti-SGSM2 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-SGSM2 antibody
SGSM2 antibody can be used for detection of SGSM2 by Western blot at 1 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-SGSM2 antibody
Western blot analysis of SGSM2 in human cerebellum tissue lysate with SGSM2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide
anti-SGSM2 antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-SGSM2 antibody
Immunofluorescence of SGSM2 in human brain tissue with SGSM2 antibody at 20 μg/mL.
anti-SGSM2 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for SGSM2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
116 kDa
NCBI Official Full Name
small G protein signaling modulator 2 isoform 1
NCBI Official Synonym Full Names
small G protein signaling modulator 2
NCBI Official Symbol
SGSM2  [Similar Products]
NCBI Official Synonym Symbols
RUTBC1
  [Similar Products]
NCBI Protein Information
small G protein signaling modulator 2; RUN and TBC1 domain containing 1; RUN and TBC1 domain-containing protein 1; small G protein signaling modulator 2 protein
UniProt Protein Name
Small G protein signaling modulator 2
UniProt Synonym Protein Names
RUN and TBC1 domain-containing protein 1
UniProt Gene Name
SGSM2  [Similar Products]
UniProt Synonym Gene Names
KIAA0397; RUTBC1  [Similar Products]
UniProt Entry Name
SGSM2_HUMAN
UniProt Comments for SGSM2
SGSM2: Belongs to the RUTBC family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 17p13.3

Molecular Function: Rab GTPase binding
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-SGSM2 antibody
 Reference Product  PubMed Publications
 SGSM3 antibody  >1 publications with SGSM2 and SGSM3
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