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anti-SRC antibody :: Rabbit SRC Polyclonal Antibody

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Catalog # MBS2530127
Unit / Price
  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Product Name

SRC, Polyclonal Antibody

Popular Item
Also Known As

SRC Polyclonal Antibody

Product Synonym Names
ASV; SRC1; c-SRC; p60-Src
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
541
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
0.5mg/mL (lot specific)
Immunogen
Recombinant protein of human SRC
Calculated Molecular Weight: 60kDa
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-SRC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SRC antibody
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Product Categories/Family for anti-SRC antibody
Applications Tested/Suitable for anti-SRC antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SRC antibody
WB: 1:200-1:1000
IHC: 1:15-1:50

Western Blot (WB) of anti-SRC antibody
Western Blot analysis of PC3 cell using SRC Polyclonal Antibody at dilution of 1:100
anti-SRC antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-SRC antibody
Immunohistochemistry of paraffin-embedded Human liver cancer using SRC Polyclonal Antibody at dilution of 1:10
anti-SRC antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-SRC antibody
Immunohistochemistry of paraffin-embedded Human esophagus cancer using SRC Polyclonal Antibody at dilution of 1:10
anti-SRC antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for SRC. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
60,645 Da
NCBI Official Full Name
Src
NCBI Official Synonym Full Names
Rous sarcoma oncogene
NCBI Official Symbol
NCBI Official Synonym Symbols
AW259666; pp60c-src
  [Similar Products]
NCBI Protein Information
neuronal proto-oncogene tyrosine-protein kinase Src; p60-Src; proto-oncogene c-Src
UniProt Protein Name
Neuronal proto-oncogene tyrosine-protein kinase Src
UniProt Synonym Protein Names
Proto-oncogene c-Src; pp60c-src; p60-Src
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
p60-Src  [Similar Products]
UniProt Entry Name
SRC_MOUSE
UniProt Comments for SRC
Src: proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme; phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme. Two alternatively spliced isoforms have been described.

Protein type: Protein kinase, tyrosine (non-receptor); Protein kinase, TK; EC 2.7.10.2; Oncoprotein; Kinase, protein; TK group; Src family

Cellular Component: extrinsic to internal side of plasma membrane; cytoskeleton; mitochondrion; membrane; perinuclear region of cytoplasm; cytoplasm; mitochondrial inner membrane; plasma membrane; actin filament; caveola; intracellular; nucleus

Molecular Function: transferase activity; protein domain specific binding; protein binding; ephrin receptor binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; non-membrane spanning protein tyrosine kinase activity; kinase activity; ATP binding; hormone receptor binding; protein kinase activity

Biological Process: epidermal growth factor receptor signaling pathway; oogenesis; regulation of estrogen receptor signaling pathway; cell migration; progesterone receptor signaling pathway; peptidyl-tyrosine phosphorylation; immune system process; regulation of cell cycle; platelet-derived growth factor receptor signaling pathway; uterus development; cell cycle; protein amino acid phosphorylation; regulation of cell proliferation; regulation of protein binding; forebrain development; innate immune response; cell adhesion; phosphorylation; bone resorption
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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