• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-SRPX antibody :: Rabbit SRPX Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS9607007
Unit / Price
Scan QR to view Datasheet
  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

SRPX, Polyclonal Antibody

Popular Item
Full Product Name

SRPX Antibody

Product Synonym Names
Down-regulated by v-SRC; DRS; DRS protein; Drs-1; Drs-2; Epididymis secretory sperm binding protein Li 83p; ETX1; EXT1; HEL S 83p; mDRS-1; mDRS-2; Srpx; SRPX_HUMAN; SRPX1; Sushi repeat containing protein, X chromosome; Sushi repeat containing protein, X linked; Sushi repeat-containing protein SRPX; Sushi-repeat-containing protein; Sushi-repeat-containing protein SRPX
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P78539
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Specificity
SRPX antibody detects endogenous levels of total SRPX
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human SRPX
Subcellular Location
Cell Surface. Possibly surface of photoreceptor cell.
Tissue Specificity
Retina and heart; less in placenta, pancreas, lung, liver, skeletal muscle, kidney and brain.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit, Dog
Similarity
Pig (91%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-SRPX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SRPX antibody
Description: X-linked retinitis pigmentosa (XLRP) is a retinal degeneration disorder. The most common form of XLRP has been localized to the gene locus RP3 by linkage and deletion analysis. RP3 maps to chromosome Xp21.1 between CYBB and OTC. The sushi-repeat-containing protein, x chromosome (SRPX) gene, also designated ETX1, resides within this region and is deleted in XLRP patients. There are at least two splice variants of SRPX, one of which contains a thirty amino acid signal peptide. Both variants contain three complement control protein domains, a hydrophobic region for membrane anchorage, and a cytoplasmic carboxy terminus. SRPX is expressed in retina and heart. SRPX is highly homologous to the drs (downregulated by v-src) human homolog, which suggests a role for SRPX as a tumor suppressor.
Function: May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction.
Applications Tested/Suitable for anti-SRPX antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-SRPX antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-SRPX antibody
MBS9607007 at 1/100 staining Human brain cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
anti-SRPX antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-SRPX antibody
Western blot analysis of HeLa lysate using SRPX antibody. The lane on the left is treated with the antigen-specific peptide.
anti-SRPX antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for SRPX. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 52 kDa
Predicted: 52 kDa
NCBI Official Full Name
sushi repeat-containing protein SRPX isoform 2
NCBI Official Synonym Full Names
sushi repeat containing protein X-linked
NCBI Official Symbol
NCBI Official Synonym Symbols
DRS; ETX1; SRPX1; HEL-S-83p
  [Similar Products]
NCBI Protein Information
sushi repeat-containing protein SRPX
UniProt Protein Name
Sushi repeat-containing protein SRPX
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Comments for SRPX
May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-SRPX antibody
 Reference Product  PubMed Publications
 CYBB antibody  >1 publications with SRPX and CYBB
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000