NP_001310245.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 77 kDa Predicted: 78 kDa
NCBI Official Full Name
protein-glutamine gamma-glutamyltransferase 2 isoform a
NCBI Official Synonym Full Names
transglutaminase 2
NCBI Official Synonym Symbols
NCBI Protein Information
protein-glutamine gamma-glutamyltransferase 2
UniProt Protein Name
Protein-glutamine gamma-glutamyltransferase 2
UniProt Synonym Protein Names
Tissue transglutaminase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase H; Transglutaminase-2; TGase-2
UniProt Synonym Gene Names
NCBI Summary for TGM2
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for TGM2
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
Research Articles on TGM2
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Pathways associated with anti-TGM2 antibody
Diseases associated with anti-TGM2 antibody
Organs/Tissues associated with anti-TGM2 antibody
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