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anti-TXN2 antibody :: Rabbit Thioredoxin Polyclonal Antibody

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Catalog # MBS1494888
Unit / Price
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  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

Thioredoxin (TXN2), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-human Thioredoxin, mitochondrial polyclonal Antibody(TXN2)

Product Synonym Names
MTRX; Mt-Trx; Thioredoxin-2; TXN2; TRX2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
609063
3D Structure
ModBase 3D Structure for Q99757
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Thioredoxin, mitochondrial protein (1-166aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22980 / sc-50336 / sc-50336
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-TXN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TXN2 antibody
Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity.
Applications Tested/Suitable for anti-TXN2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TXN2 antibody
Recommended dilution: WB:1:500-5000
IHC:1:20-1:200

Western Blot (WB) of anti-TXN2 antibody
All lanes: Thioredoxin, mitochondrial antibody at 3ug/ml
Lane 1:mouse liver tissue
Lane 2:rat brain tissue
Lane 3:mouse kidney tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 18kDa
Observed band size: 18kDa

anti-TXN2 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-TXN2 antibody
Immunohistochemistry of paraffin-embedded human tonsil using MBS1494888 at dilution 1:100
anti-TXN2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-TXN2 antibody
Immunohistochemistry of paraffin-embedded rectum using MBS1494888 at dilution 1:100
anti-TXN2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-TXN2 antibody
Immunohistochemistry of paraffin-embedded human pancreas using MBS1494888 at dilution 1:100
anti-TXN2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for TXN2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,383 Da
NCBI Official Full Name
thioredoxin, mitochondrial
NCBI Official Synonym Full Names
thioredoxin 2
NCBI Official Symbol
NCBI Official Synonym Symbols
MTRX; TRX2; MT-TRX
  [Similar Products]
NCBI Protein Information
thioredoxin, mitochondrial
UniProt Protein Name
Thioredoxin, mitochondrial
UniProt Synonym Protein Names
Thioredoxin-2
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
TRX2; MTRX; Mt-Trx  [Similar Products]
UniProt Entry Name
THIOM_HUMAN
NCBI Summary for TXN2
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008]
UniProt Comments for TXN2
TXN2: Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity. Belongs to the thioredoxin family.

Protein type: Oxidoreductase

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cell soma; dendrite; mitochondrial matrix; mitochondrion; nucleolus

Molecular Function: oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor; peptide-methionine (R)-S-oxide reductase activity; peptide-methionine-(S)-S-oxide reductase activity; protein binding; protein complex binding; protein disulfide oxidoreductase activity

Biological Process: cell redox homeostasis; cellular response to nutrient levels; glycerol ether metabolic process; protein folding; response to axon injury; response to drug; response to glucose stimulus; response to hormone stimulus; response to hypoxia; response to nutrient; response to organic cyclic substance; response to reactive oxygen species; sulfate assimilation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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