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anti-TMEM27 antibody :: Rabbit transmembrane protein 27 Polyclonal Antibody

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Catalog # MBS711479
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-TMEM27 antibody
Product Name

transmembrane protein 27 (TMEM27), Polyclonal Antibody

Popular Item
Also Known As

Rabbit anti-human transmembrane protein 27 polyclonal Antibody

Product Synonym Names
transmembrane protein 27; TMEM27; NX-17; NX17
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
222
OMIM
300631
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human TMEM27
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-135464 / sc-135465
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-TMEM27 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-TMEM27 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
NCBI/Uniprot data below describe general gene information for TMEM27. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,235 Da[Similar Products]
NCBI Official Full Name
transmembrane protein 27
NCBI Official Synonym Full Names
transmembrane protein 27
NCBI Official Symbol
TMEM27  [Similar Products]
NCBI Official Synonym Symbols
NX17; NX-17
  [Similar Products]
NCBI Protein Information
collectrin; kidney-specific membrane protein
UniProt Protein Name
Collectrin
UniProt Synonym Protein Names
Transmembrane protein 27
Protein Family
UniProt Gene Name
TMEM27  [Similar Products]
UniProt Entry Name
TMM27_HUMAN
NCBI Summary for TMEM27
This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]
UniProt Comments for TMEM27
TMEM27: Regulator of SNARE complex function. Stimulator of beta cell replication. Belongs to the TMEM27 family.

Protein type: Membrane protein, integral; Cell surface

Chromosomal Location of Human Ortholog: Xp22

Cellular Component: brush border membrane; cytoplasm; integral to membrane

Molecular Function: peptidyl-dipeptidase activity; protein binding; metallopeptidase activity

Biological Process: positive regulation of calcium ion-dependent exocytosis; proteolysis; positive regulation of amino acid transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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