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anti-UBE2L6 antibody :: Rabbit UBE2L6 Polyclonal Antibody

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Catalog # MBS9133700
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.1 mL  /  $305 +1 FREE 8GB USB
  0.2 mL  /  $460 +1 FREE 8GB USB
Western Blot (WB)
Product Name

UBE2L6, Polyclonal Antibody

Popular Item
Also Known As

UBE2L6 Polyclonal Antibody

Product Synonym Names
RIG-B; UBCH8
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
153
Immunogen Sequence
AFNLRISFPP EYPFKPPMIK FTTKIYHPNV DENGQICLPI ISSENWKPCT KTCQVLEALN VLVNRPNIRE PLRMDLADLL TQNPELFRKN AEEFTLRFGV DRPS
OMIM
3D Structure
ModBase 3D Structure for O14933
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminues of human UBE2l6 (NP_004214.1).
Calculated MW
10kDa/17kDa
Observed MW
18kDa
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-UBE2L6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-UBE2L6 antibody
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Product Categories/Family for anti-UBE2L6 antibody
Applications Tested/Suitable for anti-UBE2L6 antibody
Western Blot (WB)
Application Notes for anti-UBE2L6 antibody
WB: 1:500 - 1:2000

Western Blot (WB) of anti-UBE2L6 antibody
Western blot analysis of extracts of various cell lines, using UBE2L6 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.
anti-UBE2L6 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for UBE2L6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ubiquitin/ISG15-conjugating enzyme E2 L6 isoform 1
NCBI Official Synonym Full Names
ubiquitin conjugating enzyme E2 L6
NCBI Official Symbol
UBE2L6  [Similar Products]
NCBI Official Synonym Symbols
RIG-B; UBCH8
  [Similar Products]
NCBI Protein Information
ubiquitin/ISG15-conjugating enzyme E2 L6
UniProt Protein Name
Ubiquitin/ISG15-conjugating enzyme E2 L6
UniProt Synonym Protein Names
E2 ubiquitin-conjugating enzyme L6; Retinoic acid-induced gene B protein; RIG-B; UbcH8; Ubiquitin carrier protein L6; Ubiquitin-protein ligase L6
UniProt Gene Name
UBE2L6  [Similar Products]
UniProt Synonym Gene Names
UBCH8; RIG-B  [Similar Products]
NCBI Summary for UBE2L6
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011]
UniProt Comments for UBE2L6
Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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