NP_001291213.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 159 kDa Predicted: 159 kDa
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase 6
NCBI Official Synonym Full Names
ubiquitin specific peptidase 6
NCBI Official Synonym Symbols
HRP1; TRE2; TRE17; Tre-2; TRESMCR; USP6-short [Similar Products]
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 6
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 6
UniProt Synonym Protein Names
Deubiquitinating enzyme 6; Proto-oncogene TRE-2; Ubiquitin thioesterase 6; Ubiquitin-specific-processing protease 6
UniProt Synonym Gene Names
UniProt Comments for USP6
Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Research Articles on USP6
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Disclaimer
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Products associated with anti-USP6 antibody
Pathways associated with anti-USP6 antibody
Diseases associated with anti-USP6 antibody
Organs/Tissues associated with anti-USP6 antibody
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