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anti-RALB antibody :: Rabbit v-ral simian leukemia viral oncogene homolog B Polyclonal Antibody

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Catalog # MBS712220
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-RALB antibody
Product Name

v-ral simian leukemia viral oncogene homolog B (RALB), Polyclonal Antibody

Also Known As

Rabbit anti-human v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) polyclonal Antibody

Product Synonym Names
v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein);
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
227
OMIM
179551
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human RALB
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1531
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-RALB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-RALB antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for RALB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,710 Da[Similar Products]
NCBI Official Full Name
v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein), isoform CRA_b
NCBI Official Synonym Full Names
v-ral simian leukemia viral oncogene homolog B
NCBI Official Symbol
NCBI Protein Information
ras-related protein Ral-B; RAS-like protein B; ras related GTP binding protein B; v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)
UniProt Protein Name
Ras-related protein Ral-B
Protein Family
UniProt Gene Name
UniProt Entry Name
RALB_HUMAN
NCBI Summary for RALB
This gene encodes a GTP-binding protein that belongs to the small GTPase superfamily and Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. [provided by RefSeq, Jul 2008]
UniProt Comments for RALB
RALB: Multifuntional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis. Interacts with EXOC2 and EXOC8. Interacts with RALBP1 via its effector domain. Alternate between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase- activating protein (GAP). Belongs to the small GTPase superfamily. Ras family.

Protein type: G protein, monomeric, Ras; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: 2q14.2

Cellular Component: plasma membrane; exocyst; autophagic vacuole; midbody

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; ubiquitin protein ligase binding; ATPase binding

Biological Process: regulation of exocyst localization; positive regulation of protein binding; nerve growth factor receptor signaling pathway; apoptosis; metabolic process; regulation of exocyst assembly; Ras protein signal transduction; cytokinesis; positive regulation of protein amino acid phosphorylation; cellular response to starvation; signal transduction; negative regulation of protein binding
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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