• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-WASF1 antibody :: Rabbit WASF1 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS7053165
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

WASF1, Polyclonal Antibody

Popular Item
Also Known As

WASF1 Antibody

Product Synonym Names
Wiskott-Aldrich syndrome protein family member 1; WASP family protein member 1; Protein WAVE-1; Verprolin homology domain-containing protein 1; WASF1; KIAA0269; SCAR1; WAVE1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
559
OMIM
AF134303 mRNA
3D Structure
ModBase 3D Structure for Q92558
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Immunogen
Recombinant Human Wiskott-Aldrich syndrome protein family member 1 protein (381-553AA)
Conjugation
Non-conjugated
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-WASF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-WASF1 antibody
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
Applications Tested/Suitable for anti-WASF1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-WASF1 antibody
WB: 1:500-1:5000
IHC: 1:20-1:200

Western Blot (WB) of anti-WASF1 antibody
Western Blot
Positive WB detected in: Rat brain tissue,Mouse brain tissue
All lanes: WASF1 antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 62 KDa
Observed band size: 62 KDa

anti-WASF1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-WASF1 antibody
Immunohistochemistry of paraffin-embedded human colon cancer using MBS7053165 at dilution of 1:100
anti-WASF1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-WASF1 antibody
Immunohistochemistry of paraffin-embedded human cervical cancer using MBS7053165 at dilution of 1:100
anti-WASF1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for WASF1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
61,652 Da
NCBI Official Full Name
wiskott-Aldrich syndrome protein family member 1
NCBI Official Synonym Full Names
WAS protein family member 1
NCBI Official Symbol
WASF1  [Similar Products]
NCBI Official Synonym Symbols
WAVE; SCAR1; WAVE1
  [Similar Products]
NCBI Protein Information
wiskott-Aldrich syndrome protein family member 1
UniProt Protein Name
Wiskott-Aldrich syndrome protein family member 1
UniProt Synonym Protein Names
Protein WAVE-1; Verprolin homology domain-containing protein 1
UniProt Gene Name
WASF1  [Similar Products]
UniProt Synonym Gene Names
KIAA0269; SCAR1; WAVE1; WASP family protein member 1  [Similar Products]
NCBI Summary for WASF1
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for WASF1
WAVE1: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Belongs to the SCAR/WAVE family.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 6q21

Cellular Component: actin cytoskeleton; cytoskeleton

Molecular Function: protein binding; protein complex binding; Rac GTPase binding

Biological Process: actin filament polymerization; cell motility; Rac protein signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000