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anti-WDFY3 antibody :: Rabbit WD repeat and FYVE domain containing 3 Polyclonal Antibody

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Catalog # MBS712132
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-WDFY3 antibody
Product Name

WD repeat and FYVE domain containing 3 (WDFY3), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-human WD repeat and FYVE domain containing 3 polyclonal Antibody

Product Synonym Names
WD repeat and FYVE domain containing 3; WDFY3; ALFY; KIAA0993; MGC16461; ZFYVE25
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Immunogen
Human WDFY3
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162395
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-WDFY3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-WDFY3 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for WDFY3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
393,367 Da[Similar Products]
NCBI Official Full Name
WD repeat and FYVE domain containing 3
NCBI Official Synonym Full Names
WD repeat and FYVE domain containing 3
NCBI Official Symbol
WDFY3  [Similar Products]
NCBI Official Synonym Symbols
ALFY; ZFYVE25
  [Similar Products]
NCBI Protein Information
WD repeat and FYVE domain-containing protein 3; autophagy-linked FYVE protein
UniProt Protein Name
WD repeat and FYVE domain-containing protein 3
UniProt Synonym Protein Names
Autophagy-linked FYVE protein; Alfy
UniProt Gene Name
WDFY3  [Similar Products]
UniProt Synonym Gene Names
KIAA0993; Alfy  [Similar Products]
UniProt Entry Name
WDFY3_HUMAN
NCBI Summary for WDFY3
This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. [provided by RefSeq, May 2010]
UniProt Comments for WDFY3
WDFY3: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding; Nuclear envelope; Membrane protein, peripheral; Transferase

Chromosomal Location of Human Ortholog: 4q21.23

Cellular Component: PML body; nuclear membrane; extrinsic to membrane; cytoplasm; autophagic vacuole; nuclear envelope; inclusion body

Molecular Function: beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; protein binding; metal ion binding; phosphatidylinositol binding

Biological Process: endosome transport; positive regulation of macroautophagy
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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