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anti-YWHAG antibody :: Rabbit YWHAG Polyclonal Antibody

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Catalog # MBS2526283
Unit / Price
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  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Product Name

YWHAG, Polyclonal Antibody

Popular Item
Full Product Name

YWHAG Polyclonal Antibody

Product Synonym Names
14-3-3GAMMA
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
605356
3D Structure
ModBase 3D Structure for P61981
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
1.6mg/mL (lot specific)
Immunogen
Synthetic peptide of human YWHAG
Calculated Molecular Weight: 28kDa
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-YWHAG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-YWHAG antibody
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
Product Categories/Family for anti-YWHAG antibody
Applications Tested/Suitable for anti-YWHAG antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-YWHAG antibody
WB: 1:1000-1:5000
IHC: 1:50-1:200

Western Blot (WB) of anti-YWHAG antibody
Western Blot analysis of 293T and Jurkat cell using YWHAG Polyclonal Antibody at dilution of 1:800
anti-YWHAG antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-YWHAG antibody
Immunohistochemistry of paraffin-embedded Human lung cancer using YWHAG Polyclonal Antibody at dilution of 1:50
anti-YWHAG antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-YWHAG antibody
Immunohistochemistry of paraffin-embedded Human brain using YWHAG Polyclonal Antibody at dilution of 1:50
anti-YWHAG antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for YWHAG. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,303 Da
NCBI Official Full Name
YWHAG, partial
NCBI Official Synonym Full Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
NCBI Official Symbol
YWHAG  [Similar Products]
NCBI Official Synonym Symbols
PPP1R170; 14-3-3GAMMA
  [Similar Products]
NCBI Protein Information
14-3-3 protein gamma; 14-3-3 gamma; KCIP-1; protein kinase C inhibitor protein 1; protein phosphatase 1, regulatory subunit 170; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
UniProt Protein Name
14-3-3 protein gamma
UniProt Synonym Protein Names
Protein kinase C inhibitor protein 1; KCIP-1
Protein Family
UniProt Gene Name
YWHAG  [Similar Products]
UniProt Synonym Gene Names
KCIP-1  [Similar Products]
UniProt Entry Name
1433G_HUMAN
NCBI Summary for YWHAG
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]
UniProt Comments for YWHAG
14-3-3 gamma: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Homodimer. Interacts with SAMSN1. Interacts with RAF1, SSH1 and CRTC2/TORC2. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Interacts with GAB2. Interacts with MDM4 (phosphorylated); negatively regulates MDM4 activity toward TP53. Interacts with PKA-phosphorylated AANAT. Highly expressed in brain, skeletal muscle, and heart. Belongs to the 14-3-3 family.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: focal adhesion; cytoplasmic vesicle membrane; membrane; cytosol

Molecular Function: protein domain specific binding; insulin-like growth factor receptor binding; protein kinase C inhibitor activity; protein binding; protein kinase C binding; receptor tyrosine kinase binding

Biological Process: cellular response to insulin stimulus; apoptosis; regulation of neuron differentiation; organelle organization and biogenesis; negative regulation of protein kinase activity; regulation of synaptic plasticity; regulation of signal transduction; mitotic cell cycle; G2/M transition of mitotic cell cycle; protein targeting
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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