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anti-AACS antibody :: Rabbit anti-Human, rat AACS Polyclonal Antibody

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Catalog # MBS9211327
Unit / Price
  0.08 mL  /  $150 +1 FREE 8GB USB
  0.4 mL  /  $340 +1 FREE 8GB USB
Western Blot (WB)
Product Name

AACS, Polyclonal Antibody

Also Known As

AACS Antibody (C-term)

Product Synonym Names
Acetoacetyl-CoA synthetase; Acyl-CoA synthetase family member 1; Protein sur-5 homolog; AACS; ACSF1
Antibody/Peptide Pairs
AACS peptide (MBS9229787) is used for blocking the activity of AACS antibody (MBS9211327)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
270
OMIM
614364
3D Structure
ModBase 3D Structure for Q86V21
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human, rat
Specificity
This AACS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 539-573 amino acids from the C-terminal region of human AACS.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (lot specific)
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-AACS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AACS antibody
Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development (By similarity).
Applications Tested/Suitable for anti-AACS antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-AACS antibody
WB~~1:2000

Western Blot (WB) of anti-AACS antibody
All lanes : Anti-AACS Antibody (C-term) at 1:2000 dilution
Lane 1: human kidney lysates
Lane 2: rat brain lysates

Lysates/proteins at 20 ug per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution

Predicted band size : 75 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.
anti-AACS antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for AACS. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
75144
NCBI Official Full Name
acetoacetyl-CoA synthetase
NCBI Official Synonym Full Names
acetoacetyl-CoA synthetase
NCBI Official Symbol
NCBI Official Synonym Symbols
ACSF1; SUR-5
  [Similar Products]
NCBI Protein Information
acetoacetyl-CoA synthetase
UniProt Protein Name
Acetoacetyl-CoA synthetase
UniProt Synonym Protein Names
Acyl-CoA synthetase family member 1; Protein sur-5 homolog
UniProt Gene Name
UniProt Synonym Gene Names
ACSF1  [Similar Products]
UniProt Entry Name
AACS_HUMAN
UniProt Comments for AACS
AACS: Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development. Belongs to the ATP-dependent AMP-binding enzyme family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Ligase; EC 6.2.1.16; Carbohydrate Metabolism - butanoate

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: cytosol

Molecular Function: butyrate-CoA ligase activity; ATP binding; acetoacetate-CoA ligase activity

Biological Process: response to starvation; response to drug; response to purine; response to oleate; response to ethanol; white fat cell differentiation; positive regulation of insulin secretion; fatty acid metabolic process; liver development; response to nutrient
Product References and Citations for anti-AACS antibody
Ohgami M.,et al.Biochem. Pharmacol. 65:989-994(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gu T.,et al.Mol. Cell. Biol. 18:4556-4564(1998).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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