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anti-ANKRD1 antibody :: Rabbit anti-Human, Rat ANKRD1 Polyclonal Antibody

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Catalog # MBS7045541
Unit / Price
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  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

ANKRD1, Polyclonal Antibody

Popular Item
Full Product Name

ANKRD1 Antibody

Product Synonym Names
Ankyrin repeat domain-containing protein 1; Cardiac ankyrin repeat protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; ANKRD1; C193; CARP; HA1A2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
106700
3D Structure
ModBase 3D Structure for Q15327
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Ankyrin repeat domain-containing protein 1 protein (N-130AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23252 / sc-23251 / sc-23250 / sc-30181
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-ANKRD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ANKRD1 antibody
May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.
Applications Tested/Suitable for anti-ANKRD1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-ANKRD1 antibody
Western blot
All lanes: ANKRD1 antibody at 1.91 ug/ml
Lane 1: Rat heart tissue
Lane 2: Hela whole cell lysate
Lane 3: 293T whole cell lysate
Lane 4: Jurkat whole cell lysate
Lane 5: HepG-2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 36 kDa
Observed band size: 35 kDa

anti-ANKRD1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ANKRD1 antibody
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using MBS7045541 at dilution 1:100
anti-ANKRD1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ANKRD1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,252 Da
NCBI Official Full Name
ankyrin repeat domain-containing protein 1
NCBI Official Synonym Full Names
ankyrin repeat domain 1
NCBI Official Symbol
ANKRD1  [Similar Products]
NCBI Official Synonym Symbols
ALRP; CARP; C-193; CVARP; MCARP; bA320F15.2
  [Similar Products]
NCBI Protein Information
ankyrin repeat domain-containing protein 1
UniProt Protein Name
Ankyrin repeat domain-containing protein 1
UniProt Synonym Protein Names
Cardiac ankyrin repeat protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein
UniProt Gene Name
ANKRD1  [Similar Products]
UniProt Synonym Gene Names
C193; CARP; HA1A2  [Similar Products]
UniProt Entry Name
ANKR1_HUMAN
NCBI Summary for ANKRD1
The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system. [provided by RefSeq, Jul 2008]
UniProt Comments for ANKRD1
ANKRD1: May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. Defects in ANKRD1 may be a cause of total anomalous pulmonary venous return (TAPVR). TAPVR is a rare congenital heart disease (CHD) in which the pulmonary veins fail to connect to the left atrium during cardiac development, draining instead into either the right atrium or one of its venous tributaries. This disease accounts for 1.5% of all CHDs and has a prevalence of approximately 1 out of 15'000 live births.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 10q23.31

Cellular Component: cytoplasm; cytosol; I band; nucleolus; nucleoplasm; nucleus; sarcomere

Molecular Function: DNA binding; histone deacetylase binding; p53 binding; protein binding; titin binding; transcription corepressor activity

Biological Process: cardiac muscle morphogensis; muscle cell differentiation; positive regulation of apoptosis; positive regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of protein secretion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-ANKRD1 antibody
 Reference Product  PubMed Publications
 CASQ2 antibody  >1 publications with ANKRD1 and CASQ2
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